On the voxel size and magnetic field strength dependence of spectral resolution in magnetic resonance spectroscopy.
On the voxel size and magnetic field strength dependence of spectral resolution in magnetic resonance spectroscopy.
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DOI：
10.1016/j.mri.2008.06.009
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发表时间：
2009-02
影响因子：
2.5
通讯作者：
Gonen, Oded
中科院分区：
文献类型：
--
作者：
Fleysher, Roman;Fleysher, Lazar;Liu, Songtao;Gonen, Oded
关键词：
While the inherent low sensitivity of in vivo MR spectroscopy motivated a trend towards higher magnetic fields, B0, it since has become apparent that this increase does not seem to translate into the anticipated improvement in spectral resolution. This is attributed to the decrease of the transverse relaxation time, T2*, in vivo due to macro- and mesoscopic tissue susceptibility. Using spectral contrast to noise ratio arguments we show that if in biological systems the linewidth (on the frequency scale) increases linearly with the field, the spectral resolution (in ppm) improves approximately as the fifth-root of B0 for chemically shifted lines and decreases as about B04/5 (in Hz) for a structure of J-coupled multiplets. It is also shown that for any given B0 there is a unique voxel size that is optimal in spectral resolution, linking the spectral and spatial resolutions. Since in practical applications the spatial resolution may be dictated by the target anatomy, nomograms to determine the B0 required to achieve the desired spectral resolution at that voxel size are presented. More generally, the scaling of the nomograms to determine the achievable spectral and spatial resolutions at any given field is described.
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影响因子：
1
作者：
Tkác, I;Gruetter, R
通讯作者：
Gruetter, R
影响因子：
--
作者：
Nyquist, H
通讯作者：
Nyquist, H
影响因子：
3.3
作者：
GRUETTER, R
通讯作者：
GRUETTER, R
影响因子：
3.3
作者：
Rooney, William D.;Johnson, Glyn;Springer, Charles S., Jr.
通讯作者：
Springer, Charles S., Jr.
影响因子：
2.2
作者：
Gruetter, R;Weisdorf, SA;Ugurbil, K
通讯作者：
Ugurbil, K