Bacillus subtilis Cell Differentiation, Biofilm Formation and Environmental Prevalence.

Bacillus subtilis Cell Differentiation, Biofilm Formation and Environmental Prevalence.
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枯草芽孢杆菌的细胞分化、生物被膜形成及环境普遍性

DOI:
10.3390/microorganisms10061108
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发表时间:
2022-05-27
期刊:
影响因子:
4.5
通讯作者:
Chai, Yunrong
Chai, Yunrong
中科院分区:
生物学3区
文献类型:
--
作者:
Qin, Yuxuan;Angelini, Leticia Lima;Chai, Yunrong

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枯草芽孢杆菌是一种土生、芽胞形成、具有细胞分化能力的革兰氏阳性细菌。几十年来,枯草杆菌一直被用作研究特化细胞类型发育的模式生物。在这篇简短的综述中,我们讨论了枯草杆菌的细胞分化,包括过去的研究和最近的进展,以及细胞分化在生物膜形成中的作用和这种细菌在环境中的流行。我们回顾了枯草杆菌作为研究内孢子形成的经典模型,并重点介绍了在生物膜形成过程中细胞命运决定和多种细胞类型产生的最新研究。我们介绍了在生物膜形成过程中如何调节细胞命运决定和相互排斥的细胞分化的机制细节。
Bacillus subtilis is a soil-dwelling, spore-forming Gram-positive bacterium capable of cell differentiation. For decades, B. subtilis has been used as a model organism to study development of specialized cell types. In this minireview, we discuss cell differentiation in B. subtilis, covering both past research and recent progresses, and the role of cell differentiation in biofilm formation and prevalence of this bacterium in the environment. We review B. subtilis as a classic model for studies of endospore formation, and highlight more recent investigations on cell fate determination and generation of multiple cell types during biofilm formation. We present mechanistic details of how cell fate determination and mutually exclusive cell differentiation are regulated during biofilm formation.
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发表时间: 2010-05-04
影响因子: 11.1
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