Overweight, high blood pressure and impaired fasting glucose in Uyghur, Han, and Kazakh Chinese children and adolescents.
Overweight, high blood pressure and impaired fasting glucose in Uyghur, Han, and Kazakh Chinese children and adolescents.
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DOI：
10.1080/13557858.2014.921894
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发表时间：
2015
影响因子：
3.1
通讯作者：
Lee JH
中科院分区：
文献类型：
--
作者：
Yan WL;Li XS;Wang Q;Huang YD;Zhang WG;Zhai XH;Wang CC;Lee JH
研究中国三个不同种族儿童的血压和空腹血糖水平是否存在差异，维吾尔族、哈萨克族和汉族）以及这些差异是否可以用儿童肥胖来解释。一项以学校为基础的横断面研究在一个大的三个种族的儿科人群（n= 6，633）中进行，他们的年龄范围从7-18岁。使用标准方案测量人体测量学和血压。在根据种族和年龄随机选择的儿童亚组（n= 2，295）中测量空腹血糖。采用年龄-性别分层的中国人群临界值定义肥胖和高血压。比较了三个民族的HBP患病率、空腹血糖受损（IFG）、平均血压和血糖水平。分析了2，142名维吾尔族，2，078名汉族和1，997名哈萨克族。在调整年龄和体重指数（BMI）后，维吾尔族的平均血压平均比汉族和哈萨克族低2-4 mmHg。哈萨克族空腹血糖均值最低，汉族和维吾尔族分别为4.5、5.0和4.8mmol/L。即使在调整了年龄和BMI后，血压和空腹血糖的差异仍然存在，并且早在7至9岁时就观察到了血压水平和空腹血糖水平的种族差异。维吾尔族、汉族和哈萨克族之间HBP和IFG的患病率差异显著，儿童期观察到的种族差异与同一地区成年人观察到的差异一致。虽然儿童肥胖是高血压和血糖升高的一个重要危险因素，但种族群体之间的差异不能仅用肥胖来解释。
To investigate whether levels of blood pressure and fasting glucose differ among Chinese children of three different ethnicities (i.e., Uyghurs, Kazakhs and Hans) and whether the differences are explained by childhood obesity. A school-based cross-sectional study was conducted in a large three ethnic pediatric population (n=6,633), whose ages ranged from 7–18 years. Anthropometrics and blood pressure were measured using standard protocols. Fasting glucose was measured in a subset of children (n=2,295) who were randomly selected based on ethnicity and age. The age-sex stratified Chinese national cutoffs were used to define obesity and high blood pressure (HBP). The prevalence of HBP, impaired fasting glucose (IFG), mean levels of blood pressure and glucose were compared among three ethnic groups. 2,142 Uyghurs, 2,078 Han and 1,997 Kazakhs were analyzed. After adjusting for age and body mass index (BMI), the mean blood pressure for Uyghurs was on average, 2–4 mmHg lower than those for Hans and Kazakhs. Kazakhs had the lowest mean fasting glucose compared with Hans and Uyghurs (4.5 vs 5.0 vs. 4.8mmol/L, respectively). The differences in blood pressure and fasting glucose persisted even after adjusting for age and BMI, and the differences among ethnic groups in blood pressure levels and fasting glucose levels were observed as early as 7 to 9 years of age. The prevalence of HBP and IFG differed significantly among Uyghurs, Hans and Kazakhs, and the ethnic differences observed in childhood were consistent with those observed in adults from the same region. While childhood obesity is a significant risk factor for hypertension and elevated glucose, the differences among ethnic groups were not explained by obesity alone.
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影响因子：
5.1
作者：
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通讯作者：
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