Self-medication with antibiotics in rural population in Greece: a cross-sectional multicenter study.
Self-medication with antibiotics in rural population in Greece: a cross-sectional multicenter study.
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DOI：
10.1186/1471-2296-11-58
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发表时间：
2010-08-08
影响因子：
2.9
通讯作者：
Sotiropoulos A
中科院分区：
文献类型：
--
作者：
Skliros E;Merkouris P;Papazafiropoulou A;Gikas A;Matzouranis G;Papafragos C;Tsakanikas I;Zarbala I;Vasibosis A;Stamataki P;Sotiropoulos A
自我用药是抗菌药物过度使用的一个重要驱动因素，也是一个全球性问题。本研究的目的是估计在希腊南部农村人口的初级保健样本中，抗生素的使用情况，没有医疗处方。该研究纳入了1139名随机选择的成年人（545名男性/594名女性，平均年龄±SD: 56.2±19.8岁）的数据，这些成年人在2009年11月至2010年1月期间访问了希腊南部的6个农村卫生中心。符合条件的参与者以一对一的方式被寻找出来，并被要求回答一份匿名问卷。888名参与者（77.9%）报告在过去12个月内使用过抗生素。508人（44.6%）报告至少一次在没有医生处方的情况下使用抗生素。自我药疗的主要来源为无处方药房（76.2%）。自我药疗使用最多的抗生素是阿莫西林（18.3%）、阿莫西林/克拉维酸（15.4%）、头孢克洛（9.7%）、头孢呋辛（7.9%）、头孢丙烯（4.7%）和环丙沙星（2.3%）。发热（41.2%）、普通感冒（32.0%）和喉咙痛（20.6%）是使用自行给药抗生素的最常见适应症。在希腊，尽管有开放和快速获得初级保健服务的机会，但似乎有很大比例的农村成年人口在没有医疗处方的情况下使用抗生素，尤其是用于发烧和普通感冒。
Self-medication is an important driver of antimicrobial overuse as well as a worldwide problem. The aim of the present study was to estimate the use of antibiotics, without medical prescription, in a sample of rural population presenting in primary care in southern Greece. The study included data from 1,139 randomly selected adults (545 men/594 women, mean age ± SD: 56.2 ± 19.8 years), who visited the 6 rural Health Centres of southern Greece, between November 2009 and January 2010. The eligible participants were sought out on a one-to-one basis and asked to answer an anonymous questionnaire. Use of antibiotics within the past 12 months was reported by 888 participants (77.9%). 508 individuals (44.6%) reported that they had received antibiotics without medical prescription at least one time. The major source of self-medication was the pharmacy without prescription (76.2%). The antibiotics most frequently used for self-medication were amoxicillin (18.3%), amoxicillin/clavulanic acid (15.4%), cefaclor (9.7%), cefuroxim (7.9%), cefprozil (4.7%) and ciprofloxacin (2.3%). Fever (41.2%), common cold (32.0%) and sore throat (20.6%) were the most frequent indications for the use of self-medicated antibiotics. In Greece, despite the open and rapid access to primary care services, it appears that a high proportion of rural adult population use antibiotics without medical prescription preferably for fever and common cold.
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DOI：
10.1016/j.ijantimicag.2005.02.009
发表时间：
2005-05-01
影响因子：
10.8
作者：
Mitsi, G;Jelastopulu, E;Gogos, C
通讯作者：
Gogos, C
影响因子：
11.8
作者：
de Sande-Bruinsma, Nienke Van;Grundmann, Hajo;Verloo, Didier;Tiemersma, Edine;Monen, Jos;Goossens, Herman;Ferech, Matus
通讯作者：
Ferech, Matus
影响因子：
5.2
作者：
Grigoryan, Larissa;Burgerhof, Johannes G. M.;Haaijer-Ruskamp, Flora M.
通讯作者：
Haaijer-Ruskamp, Flora M.
影响因子：
5.2
作者：
McNulty, Cliodna A. M.;Johnson, Alan P.
通讯作者：
Johnson, Alan P.
影响因子：
3.3
作者：
Väändnen, MH;Pietilä, K;Airaksinen, M
通讯作者：
Airaksinen, M