Antimicrobial drug use and resistance in Europe.
Antimicrobial drug use and resistance in Europe.
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DOI:
10.3201/eid1411.070467
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发表时间:
2008-11
影响因子:
11.8
通讯作者:
Ferech, Matus
中科院分区:
文献类型:
--
作者:
de Sande-Bruinsma, Nienke Van;Grundmann, Hajo;Verloo, Didier;Tiemersma, Edine;Monen, Jos;Goossens, Herman;Ferech, Matus
Routine surveillance data indicate a relation between use and resistance and support interventions designed to reduce antimicrobial consumption at a national level in Europe. Our study confronts the use of antimicrobial agents in ambulatory care with the resistance trends of 2 major pathogens, Streptococcus pneumoniae and Escherichia coli, in 21 European countries in 2000–2005 and explores whether the notion that antimicrobial drug use determines resistance can be supported by surveillance data at national aggregation levels. The data obtained from the European Surveillance of Antimicrobial Consumption and the European Antimicrobial Resistance Surveillance System suggest that variation of consumption coincides with the occurrence of resistance at the country level. Linear regression analysis showed that the association between antimicrobial drug use and resistance was specific and robust for 2 of 3 compound pathogen combinations, stable over time, but not sensitive enough to explain all of the observed variations. Ecologic studies based on routine surveillance data indicate a relation between use and resistance and support interventions designed to reduce antimicrobial drug consumption at a national level in Europe.
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影响因子:
5.2
作者:
Bruinsma, N;Kristinsson, KG;Grundmann, H
通讯作者:
Grundmann, H
影响因子:
11.8
作者:
Tiemersma EW;Bronzwaer SL;Lyytikäinen O;Degener JE;Schrijnemakers P;Bruinsma N;Monen J;Witte W;Grundman H;European Antimicrobial Resistance Surveillance System Participants
通讯作者:
European Antimicrobial Resistance Surveillance System Participants
DOI:
10.1016/s0924-8579(03)00239-5
发表时间:
2003-11-01
影响因子:
10.8
作者:
García-Rey, C;Bouza, E;Baquero, F
通讯作者:
Baquero, F
影响因子:
11.8
作者:
Harbarth, S;Albrich, W;Brun-Buisson, C
通讯作者:
Brun-Buisson, C
影响因子:
11.8
作者:
Steinke, D;Davey, P
通讯作者:
Davey, P