Role of neutrophils in acute viral infection.
Role of neutrophils in acute viral infection.
复制标题
中性粒细胞在急性病毒感染中的作用
DOI:
10.1002/iid3.500
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发表时间:
2021-12
期刊:
影响因子:
--
通讯作者:
Zhu L
中科院分区:
文献类型:
--
作者:
Ma Y;Zhang Y;Zhu L
Neutrophils play multiple roles in acute viral infections. They restrict viral replication and diffusion through phagocytosis, degranulation, respiratory burst, secretion of cytokines, and the release of neutrophil extracellular traps, as well as, activate the adaptive immune response. However, the overactivation of neutrophils may cause tissue damage and lead to poor outcomes. Additionally, some characteristics and functions of neutrophils, such as cell number, lifespan, and antiviral capability, can be influenced while eliminating viruses. This review provides a general description of the protective and pathological roles of neutrophils in acute viral infection.
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