TRPC2 and the Molecular Biology of Pheromone Detection in Mammals

TRPC2 and the Molecular Biology of Pheromone Detection in Mammals
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TRPC2 和哺乳动物信息素检测的分子生物学

DOI:
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发表时间:
2007
期刊:
影响因子:
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通讯作者:
C. Dulac
C. Dulac
中科院分区:
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文献类型:
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作者:
E. Liman;C. Dulac

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TRPC2 通道在啮齿动物中的表达似乎主要局限于犁鼻器 (VNO) 的神经元,并且在少数其他组织中检测到较低水平。 TRPC2 表达的特征以及 TRPC2 基因作为遗传操作工具的可用性,在了解啮齿类动物和整个进化过程中犁鼻器器官和信息素检测的生物学方面取得了重大进展。
The expression of the TRPC2 channel in rodents appears largely restricted to neurons of the vomeronasal organ (VNO) and is detected at lower levels in few other tissues. The characteristics of TRPC2 expression, as well as the availability of the TRPC2 gene as a tool for genetic manipulation, has led to significant advances in understanding the biology of the vomeronasal organ and pheromone detection in rodents and across evolution.
DOI: 10.1073/pnas.92.21.9652
发表时间: 1995-10-10
影响因子: 11.1
作者:
WES, PD;CHEVESICH, J;MONTELL, C
通讯作者: MONTELL, C