Short-term inhibition of spinal reflexes in multiple lower limb muscles after neuromuscular electrical stimulation of ankle plantar flexors
Short-term inhibition of spinal reflexes in multiple lower limb muscles after neuromuscular electrical stimulation of ankle plantar flexors
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神经肌肉电刺激踝跖屈肌后短期抑制下肢多块肌肉的脊髓反射
DOI：
10.1007/s00221-018-5437-6
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发表时间：
2018
影响因子：
2
通讯作者：
Nakazawa Kimitaka
中科院分区：
文献类型：
--
作者：
Milosevic Matija;Masugi Yohei;Obata Hiroki;Sasaki Atsushi;Popovic Milos R.;Nakazawa Kimitaka
神经肌肉电刺激(NMES)通过激活传出纤维和伴随的传入纤维募集引起肌肉收缩，从而调节中枢神经系统的兴奋性。然而，NMES的神经机制以及刺激单侧比目鱼肌如何影响双侧多条腿肌的脊髓反射仍不清楚。选取12名健康受试者，对S的右侧足底屈肌进行4种干预，每组60例，分别测定脊髓反射兴奋性的变化：(1)运动性NMES；(2)感觉性NMES；(3)自主收缩；(4)休息。采用单脉冲经皮脊髓刺激在脊髓腰段诱发双侧双侧肢体肌肉反应，刺激比目鱼肌测定最大运动反应(MMAX)。将每次干预前的脊髓反射和最大值与干预后即刻和随后每隔5分钟进行比较，持续15分钟。结果显示，运动水平的NMES抑制比目鱼肌和同侧小腿其他研究肌肉的脊髓反射15分钟，但不抑制对侧小腿(除股内侧肌)的脊髓反射，也不影响比目鱼肌的肌肉特性(MMAX)。自主收缩效应持续时间不到5分钟，而感觉水平的NMES和休息没有产生影响。短期脊髓反射兴奋性可能受到影响，因为在运动水平的NMES过程中，脊髓中的逆行冲动与诱发脊髓神经可塑性的传入输入重合，而单独的传入输入不会产生短期效果。NMES对肌肉的这种激活可以减少有神经损伤的人的痉挛。
Neuromuscular electrical stimulation (NMES) of lower limbs elicits muscle contractions through the activation of efferent fibers and concomitant recruitment of afferent fibers, which can modulate excitability of the central nervous system. However, neural mechanisms of NMES and how unilateral stimulation of the soleus affects spinal reflexes in multiple lower limb muscles bilaterally remains unknown. Twelve able-bodied participants were recruited, and spinal reflex excitability changes were tested after four interventions, each applied for 60 s, on the right plantar flexors: (1) motor-level NMES; (2) sensory-level NMES; (3) voluntary contraction; (4) rest. Spinal reflexes were elicited using single-pulse transcutaneous spinal cord stimulation applied on the lumbar level of the spinal cord to evoke bilateral responses in multiple lower limb muscles, while maximum motor response (Mmax) was tested in the soleus by stimulating the posterior tibial nerve. Spinal reflexes andMmaxbefore each intervention were compared to immediately after and every 5 min subsequently, for 15 min. Results showed that motor-level NMES inhibited spinal reflexes of the soleus and other studied muscles of the ipsilateral leg, but not the contralateral leg (except vastus medialis) for 15 min, while not affecting soleus muscle properties (Mmax). Voluntary contraction effect lasted less than 5 min, while sensory-level NMES and rest did not produce an effect. Short-term spinal reflex excitability was likely affected because antidromic impulses during motor-level NMES coincided in the spinal cord with afferent inputs to induce spinal neuroplasticity, whereas afferent input alone did not produce short-term effects. Such activation of muscles with NMES could reduce spasticity in individuals with neurological impairments.
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影响因子：
4.2
作者：
Stein, Richard B.;Everaert, Dirk G.;Kuether, Gerald
通讯作者：
Kuether, Gerald
狒狒 F 波的实验研究。
影响因子：
11
作者：
J. McLeod;S. Wray
通讯作者：
S. Wray
影响因子：
2
作者：
Barbeau, H;Marchand-Pauvert, V;Pierrot-Deseilligny, E
通讯作者：
Pierrot-Deseilligny, E
人类从比目鱼肌到股四头肌运动神经元的异同脊髓循环抑制通路中的传递的任务相关变化。
DOI：
10.1093/brain/123.11.2264
发表时间：
2000
期刊：
Brain : a journal of neurology
影响因子：
--
作者：
J. Iles;A. Ali;J. Pardoe
通讯作者：
J. Pardoe
影响因子：
2
作者：
Crone, C;Johnsen, LL;Orsnes, GB
通讯作者：
Orsnes, GB