Use of explicit memory cues following parietal lobe lesions.
Use of explicit memory cues following parietal lobe lesions.
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DOI：
10.1016/j.neuropsychologia.2012.07.037
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发表时间：
2012-11
期刊：
影响因子：
2.6
通讯作者：
Simons JS
中科院分区：
文献类型：
--
作者：
Dobbins IG;Jaeger A;Studer B;Simons JS
侧顶叶在情景记忆中的假定作用最近已成为一个相当大的争论的话题，主要是由于其一致的激活研究材料在功能磁共振成像研究的识别。在这里，我们研究了患者的表现顶叶病变使用外显记忆提示任务中的概率线索（“可能旧”或“可能新”，75%的有效性）之前，大多数的口头识别记忆探针。在没有提示的情况下，患者和对照组参与者在准确性上没有差异。然而，组间差异出现在“可能新的”提示条件与控制响应更准确地比顶叶患者时，这些线索是有效的（前新材料）和倾向于不太准确，当这些线索是无效的（前旧材料）。这两种效果表明，外部线索整合到记忆判断的一部分，顶叶患者的线索性能在很大程度上类似于性能完全没有线索。顶叶患者与额叶病变患者组的比较表明，顶叶和邻近区域病变的模式是特定的。总的来说，数据表明，顶叶患者未能适当地将外部线索的新奇性识别归因。这一发现支持的作用，侧顶叶在记忆判断的自适应偏见，通过整合外部线索和内部记忆证据。我们概述了这样的自适应偏置的重要性，通过考虑基本信号检测预测最大可能的准确性，有和没有信息丰富的环境线索。
The putative role of the lateral parietal lobe in episodic memory has recently become a topic of considerable debate, owing primarily to its consistent activation for studied materials during functional magnetic resonance imaging studies of recognition. Here we examined the performance of patients with parietal lobe lesions using an explicit memory cueing task in which probabilistic cues (“Likely Old” or “Likely New”; 75% validity) preceded the majority of verbal recognition memory probes. Without cues, patients and control participants did not differ in accuracy. However, group differences emerged during the “Likely New” cue condition with controls responding more accurately than parietal patients when these cues were valid (preceding new materials) and trending towards less accuracy when these cues were invalid (preceding old materials). Both effects suggest insufficient integration of external cues into memory judgments on the part of the parietal patients whose cued performance largely resembled performance in the complete absence of cues. Comparison of the parietal patients to a patient group with frontal lobe lesions suggested the pattern was specific to parietal and adjacent area lesions. Overall, the data indicate that parietal lobe patients fail to appropriately incorporate external cues of novelty into recognition attributions. This finding supports a role for the lateral parietal lobe in the adaptive biasing of memory judgments through the integration of external cues and internal memory evidence. We outline the importance of such adaptive biasing through consideration of basic signal detection predictions regarding maximum possible accuracy with and without informative environmental cues.
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