Ocean acidification influences host DNA methylation and phenotypic plasticity in environmentally susceptible corals.
Ocean acidification influences host DNA methylation and phenotypic plasticity in environmentally susceptible corals.
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DOI：
10.1111/eva.12408
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发表时间：
2016-10
影响因子：
4.1
通讯作者：
Gates RD
中科院分区：
文献类型：
--
作者：
Putnam HM;Davidson JM;Gates RD
随着气候变化通过创造表型-环境失配来挑战生物体适应性，表观遗传机制（例如，DNA甲基化）可以为遗传适应提供时间缓冲。表观遗传机制可能对固着底栖海洋生物至关重要，例如造礁珊瑚，海洋酸化（OA）和变暖反映了强烈的负面反应。我们测试了骨珊瑚表现出表型可塑性的潜力与DNA甲基化的变化，以响应OA。将环境敏感的Pocillopora damicornis和环境更健壮的Montipora capitata的克隆珊瑚碎片暴露于普通花园水箱中的波动环境pH值（7.9-7.65）和低pH值（7.6-7.35）条件下约6周。M. capitata对OA的反应较弱，或适应更快，在钙化方面没有差异，代谢组学特征的分离最小，处理之间的DNA甲基化没有变化。相反，P. damicornis在低pH值下表现出钙化减少，代谢组学谱的分离更强，DNA甲基化对治疗的反应性。我们的数据表明，珊瑚的时间动态和对环境触发的真实的时间表观遗传重编程的敏感性不同。通过环境诱导DNA甲基化产生潜在的遗传可塑性，为快速气候变化下珊瑚的辅助进化应用提供了一条途径。
As climate change challenges organismal fitness by creating a phenotype–environment mismatch, phenotypic plasticity generated by epigenetic mechanisms (e.g., DNA methylation) can provide a temporal buffer for genetic adaptation. Epigenetic mechanisms may be crucial for sessile benthic marine organisms, such as reef‐building corals, where ocean acidification (OA) and warming reflect in strong negative responses. We tested the potential for scleractinian corals to exhibit phenotypic plasticity associated with a change in DNA methylation in response to OA. Clonal coral fragments of the environmentally sensitive Pocillopora damicornis and more environmentally robust Montipora capitata were exposed to fluctuating ambient pH (7.9–7.65) and low pH (7.6–7.35) conditions in common garden tanks for ~6 weeks. M. capitata responded weakly, or acclimated more quickly, to OA, with no difference in calcification, minimal separation of metabolomic profiles, and no change in DNA methylation between treatments. Conversely, P. damicornis exhibited diminished calcification at low pH, stronger separation in metabolomic profiles, and responsiveness of DNA methylation to treatment. Our data suggest corals differ in their temporal dynamics and sensitivity for environmentally triggered real‐time epigenetic reprogramming. The generation of potentially heritable plasticity via environmental induction of DNA methylation provides an avenue for assisted evolution applications in corals under rapid climate change.
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影响因子：
2.9
作者：
Al-Sofyani, Abdulmohsin A.;Floos, Yahya A. M.
通讯作者：
Floos, Yahya A. M.
DOI：
10.1038/nrg3355
发表时间：
2013-02
期刊：
Nature reviews. Genetics
影响因子：
--
作者：
通讯作者：
--
影响因子：
4.4
作者：
Dixon GB;Bay LK;Matz MV
通讯作者：
Matz MV
影响因子：
4.5
作者：
Comeau, S.;Edmunds, P. J.;Carpenter, R. C.
通讯作者：
Carpenter, R. C.
影响因子：
5.2
作者：
Anthony, KRN;Hoegh-Guldberg, O
通讯作者：
Hoegh-Guldberg, O