Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission Dynamics Should Inform Policy.

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission Dynamics Should Inform Policy.
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DOI:
10.1093/cid/ciaa1442
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发表时间:
2021-07-30
期刊:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子:
--
通讯作者:
Smith TC
Smith TC
中科院分区:
其他
文献类型:
--
作者:
Cevik M;Marcus JL;Buckee C;Smith TC

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人们普遍认为,在恢复经济和社会活动与使用非药物干预措施将有效生殖数(R 0)保持在1以下之间取得平衡,是一个重要的目标,直到甚至在有效疫苗问世之后。因此,仍然需要了解病毒是如何传播的,以便查明高风险环境和不成比例地助长其传播的活动,从而能够采取有效的预防措施。特别是接触者追踪和家庭研究提供了关于传播参数的有力证据。在本观点中,我们讨论了来自世界各地的大规模、良好的接触者追踪研究的现有证据,并认为严重急性呼吸系统综合征冠状病毒2(SARS-CoV-2)传播动态应通过将注意力集中在环境、活动以及与最高传播风险相关的社会经济因素。
It is generally agreed that striking a balance between resuming economic and social activities and keeping the effective reproductive number (R0) below 1 using nonpharmaceutical interventions is an important goal until and even after effective vaccines become available. Therefore, the need remains to understand how the virus is transmitted in order to identify high-risk environments and activities that disproportionately contribute to its spread so that effective preventative measures could be put in place. Contact tracing and household studies, in particular, provide robust evidence about the parameters of transmission. In this Viewpoint, we discuss the available evidence from large-scale, well-conducted contact-tracing studies from across the world and argue that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission dynamics should inform policy decisions about mitigation strategies for targeted interventions according to the needs of the society by directing attention to the settings, activities, and socioeconomic factors associated with the highest risks of transmission.
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