Lexical and semantic priming deficits in patients with Alzheimer's disease.
Lexical and semantic priming deficits in patients with Alzheimer's disease.
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阿尔茨海默病患者的词汇和语义启动缺陷。
DOI：
10.1080/01688638808408254
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发表时间：
1988
影响因子：
2.2
通讯作者：
Smith,S
中科院分区：
文献类型：
--
作者：
Salmon,DP;Shimamura,AP;Butters,N;Smith,S
两项利用启动程序的实验检查了痴呆和健忘症患者的语义记忆状态。在第一项研究中，对阿尔茨海默型痴呆 (DAT)、亨廷顿病 (HD)、酒精性科尔萨科夫综合征 (KS) 患者和完整对照受试者的词汇启动进行了评估。受试者首先在评分任务中接触到一系列单词，然后要求他们用“想到的第一个单词”完成三个字母的词干。一半的词干可以用之前提出的单词来完成，另一半用于评估基线猜测率。还评估了对偶然暴露的单词的回忆和识别。尽管所有三个患者组在回忆和识别测试中均受到损害，但只有 DAT 患者在干完成任务上表现出启动缺陷。在第二个实验中，DAT、HD 和完整对照受试者接受了语义启动测试，该测试要求受试者“自由联想”先前呈现的语义相关单词对的第一个单词。这项关联任务的结果表明，与其他受试者组相比，DAT 患者产生语义相关对的第二个单词的可能性明显较低。这两个实验的结果表明，DAT 患者的记忆能力的特点是语义记忆结构的崩溃，并且这种损害在一些“自动”和“费力”的处理任务中很明显。
Two experiments utilizing priming procedures examined the status of semantic memory in demented and amnesic patients. In the first investigation, lexical priming was assessed in patients with dementia of the Alzheimer type (DAT), Huntington's Disease (HD), alcoholic Korsakoff's syndrome (KS), and in intact control subjects. Subjects were first exposed to a list of words in a rating task and then required to complete three-letter stems with the “first word that comes to mind”. Half of the stems could be completed with the previously presented words and the other half were used to assess baseline guessing rates. Recall and recognition of incidentally exposed words was also assessed. Although all three patient groups were impaired on tests of recall and recognition, only the DAT patients exhibited a priming deficit on the stem-completion task. In the second experiment, DAT, HD, and intact control subjects were administered a semantic priming test which required the subject to “free associate” to the first words of previously presented semantically associated word pairs. The results for this association task showed that DAT patients were significantly less likely to produce the second word of the semantically related pair than were the other subject groups. The results of these two experiments suggest that the memory capacities of DAT patients are characterized by a breakdown in the structure of semantic memory and that this impairment is evident on some “automatic” as well as “effortful” processing tasks.
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老年痴呆症的诊断和治疗。
DOI：
--
发表时间：
1981
期刊：
Western Journal of Medicine
影响因子：
--
作者：
Gary W. Small;Liston Eh;Lissy F. Jarvik
通讯作者：
Lissy F. Jarvik
DOI：
10.1037//0278-7393.10.1.164
发表时间：
1984
期刊：
Journal of experimental psychology. Learning, memory, and cognition
影响因子：
--
作者：
P. Graf;L. Squire;G. Mandler
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P. Graf;L. Squire;G. Mandler
失忆症的启动效应：分离记忆功能的证据
DOI：
--
发表时间：
1986
期刊：
The Quarterly journal of experimental psychology. A, Human experimental psychology
影响因子：
--
作者：
A. Shimamura
通讯作者：
A. Shimamura
痴呆症的临床和神经心理学评估
DOI：
--
发表时间：
1986
期刊：
影响因子：
--
作者：
F. Huppert;E. Tym
通讯作者：
E. Tym
痴呆和健忘症中的记忆功能障碍和单词启动。
影响因子：
1.9
作者：
Shimamura,AP;Salmon,DP;Squire,LR;Butters,N
通讯作者：
Butters,N