The cardiometabolic profile and related dietary intake of Ugandans living with HIV and AIDS.
The cardiometabolic profile and related dietary intake of Ugandans living with HIV and AIDS.
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DOI：
10.3389/fnut.2022.976744
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发表时间：
2022
影响因子：
5
通讯作者：
Matthys, Christophe
中科院分区：
文献类型：
--
作者：
Kiyimba, Tonny;Kigozi, Fred;Yiga, Peter;Mukasa, Barbara;Ogwok, Patrick;Van der Schueren, Bart;Matthys, Christophe
不理想的饮食和缺乏身体活动降低了艾滋病毒感染者（PLWH）抗逆转录病毒治疗（ART）的预期益处。然而，在乌干达，关于艾滋病毒携带者的饮食摄入和心脏代谢特征的文献很少。在乌干达的艾滋病毒携带者中进行了一项横断面研究。采用非连续2天的24小时回忆法评估饮食摄入量。简短的国际体力活动问卷评估了参与者的体力活动。分析空腹血样的空腹血糖（FBG）、总胆固醇、LDL-c、HDL-c和甘油三酯。按照WHO STEPS第2步进行血压和人体测量。253例患者完成了本研究。低HDL-c（31.9%）、腹型肥胖（44.5%）、高BMI（51.6%）、FBG升高（45.3%）、高SBP（31.5%）、甘油三酯升高（26.4%）和代谢综合征（28%）的患病率较高，女性代谢综合征患病率（31.5%）高于男性（19.2%）。高LDL-c（4.7%）和高总胆固醇（9.8%）的发生率较低，膳食中碳水化合物（65.8 ± 10.4）E%和纤维摄入量（30.1 ± 12.7）g较高，多不饱和脂肪酸（6.1 ± 2.3）E%和水果蔬菜摄入量（1.4份）较低。维生素A（38.2%）、B1（48.8%）、B2（29.6%）、B12（29%）、叶酸（61.4%）、Ca（76%）、Zn（53.1%）和Mg（41.7%）的摄入量未满足比例较高。平均MET min为6，700 ± 5，509，超过68%的参与者MET min> 3，000。我们的研究结果显示，乌干达PLWH中代谢紊乱的患病率很高，并进一步强调他们的饮食不理想，水果和蔬菜摄入量低
Suboptimal diet and physical inactivity downgrade the putative benefits of Antiretroviral Therapy (ART) among People Living with HIV (PLWH). However, there is paucity of literature on dietary intake and cardiometabolic profiles of PLWH in Uganda. A cross-sectional study among PLWH in Uganda was conducted. Dietary intake was assessed using a 24h recall method of 2 non-consecutive days. The short International Physical Activity Questionnaire assessed participants' physical activity. Fasted blood samples were analyzed for Fasting Blood Glucose (FBG), total cholesterol, LDL-c, HDL-c and triglycerides. Blood pressure and anthropometric measurements were performed following step 2 of the WHO STEPS. 253 patients completed in this study. A high prevalence of low HDL-c (31.9%), abdominal obesity (44.5%), high BMI (51.6%), raised FBG (45.3%), high SBP (31.5%), elevated triglycerides (26.4%) and metabolic syndrome (28%) was found. More women were identified with metabolic syndrome (31.5%) than men (19.2%). Low prevalence of high LDL-c (4.7%) and total cholesterol (9.8%) was found. Diets had a high carbohydrate (65.8 ± 10.4) E% and fiber intake (30.1 ± 12.7) g with minimal PUFA (6.1 ± 2.3) E%, fruits and vegetables (1.4 servings). High proportions were found of unmet intake for vitamin A (38.2%), B1(48.8%), B2 (29.6%), B12 (29%), folate (61.4%), Ca (76%), Zn (53.1%) and Mg (41.7%). Mean MET min was 6,700 ± 5,509 and over 68% of the participants had >3,000 MET min. Our findings reveal a high prevalence of metabolic disturbances among PLWH in Uganda and further highlight that their diets are suboptimal with low fruits and vegetable intake
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影响因子：
3.7
作者：
Crum-Cianflone N;Roediger MP;Eberly L;Headd M;Marconi V;Ganesan A;Weintrob A;Barthel RV;Fraser S;Agan BK;Infectious Disease Clinical Research Program HIV Working Group
通讯作者：
Infectious Disease Clinical Research Program HIV Working Group
影响因子：
7.7
作者：
Dillon DG;Gurdasani D;Riha J;Ekoru K;Asiki G;Mayanja BN;Levitt NS;Crowther NJ;Nyirenda M;Njelekela M;Ramaiya K;Nyan O;Adewole OO;Anastos K;Azzoni L;Boom WH;Compostella C;Dave JA;Dawood H;Erikstrup C;Fourie CM;Friis H;Kruger A;Idoko JA;Longenecker CT;Mbondi S;Mukaya JE;Mutimura E;Ndhlovu CE;Praygod G;Pefura Yone EW;Pujades-Rodriguez M;Range N;Sani MU;Schutte AE;Sliwa K;Tien PC;Vorster EH;Walsh C;Zinyama R;Mashili F;Sobngwi E;Adebamowo C;Kamali A;Seeley J;Young EH;Smeeth L;Motala AA;Kaleebu P;Sandhu MS;African Partnership for Chronic Disease Research (APCDR)
通讯作者：
African Partnership for Chronic Disease Research (APCDR)
影响因子：
4.2
作者：
Haubrock, Jennifer;Noethlings, Ute;Boeing, Heiner
通讯作者：
Boeing, Heiner
影响因子：
7
作者：
Audain, Keiron A.;Zotor, Francis B.;Ellahi, Basma
通讯作者：
Ellahi, Basma
影响因子：
3.2
作者：
Hagstromer, Maria;Oja, Pekka;Sjostrom, Michael
通讯作者：
Sjostrom, Michael