Magneto-Elastic μ-Vibrator for Smashing Thrombus
Magneto-Elastic μ-Vibrator for Smashing Thrombus
复制标题
用于粉碎血栓的磁弹性μ振动器
DOI：
10.3390/mi10010074
复制
发表时间：
2019
期刊：
影响因子：
3.4
通讯作者：
Xinxin Li
中科院分区：
文献类型：
--
作者：
Wei Li;C. Xue;Xinxin Li
本研究提出并发展一种小型化血栓疏通器。微共振挖泥船的弯曲共振是由交变磁场激励的体拉伸磁弹性振子驱动的。利用所研制的共振疏通器样机，将堵塞在模拟血管中的小鼠血栓破碎成微小碎片，使堵塞的血管在1 h内恢复通畅。采用流速比检测法评价血栓清除效果。通过有限元仿真与实验结果的对比，验证了流量比检测方法的有效性。通过在第三共振模式下最佳地激励共振疏通器，与部分阻塞的血管相比，清洁的血管中的流速比增加约2.7倍，并且血栓被粉碎成微小碎片。
A miniaturized thrombus dredger is proposed and developed in this study. The flexural resonance of the µ-resonator dredger is driven by a bulk-extensional magneto-elastic vibrator that is externally excited by alternating magnetic-field. With the fabricated prototype of the resonant dredger, a mice thrombus blocked in a simulated vessel is broken into micro-pieces, and the previously blocked vessel can recover to an unobstructed state within 1 h. A flow-rate ratio detection method is used to evaluate the thrombus-cleaning effectiveness. The comparison between the finite-element simulation and the experimental results validates the flow-rate ratio detection method. By optimally exciting the resonant dredger in its third resonant mode, the flow-rate ratio in the cleaned vessel increases by about 2.7 times compared with that in the partly blocked vessel, and the thrombus is smashed into micro-pieces.
DOI：
10.3233/jae-2006-805
发表时间：
2006
影响因子：
0.6
作者：
Zhongwei Jiang;M. Morita;Tetsuyou Watanabe;S. Kato;Michiyasu Suzuki
通讯作者：
Zhongwei Jiang;M. Morita;Tetsuyou Watanabe;S. Kato;Michiyasu Suzuki