Whole genome transcriptome polymorphisms in Arabidopsis thaliana.
Whole genome transcriptome polymorphisms in Arabidopsis thaliana.
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DOI:
10.1186/gb-2008-9-11-r165
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发表时间:
2008
期刊:
影响因子:
12.3
通讯作者:
Borevitz, Justin O.
中科院分区:
文献类型:
--
作者:
Zhang, Xu;Byrnes, Jake K.;Gal, Thomas S.;Li, Wen-Hsiung;Borevitz, Justin O.
New methods for detecting global patterns of gene expression and splicing variation in natural Arabidopsis thaliana populations. Whole genome tiling arrays are a key tool for profiling global genetic and expression variation. In this study we present our methods for detecting transcript level variation, splicing variation and allele specific expression in Arabidopsis thaliana. We also developed a generalized hidden Markov model for profiling transcribed fragment variation de novo. Our study demonstrates that whole genome tiling arrays are a powerful platform for dissecting natural transcriptome variation at multi-dimension and high resolution.
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