Willingness of men who have sex with men (MSM) in the United States to be circumcised as adults to reduce the risk of HIV infection.

Willingness of men who have sex with men (MSM) in the United States to be circumcised as adults to reduce the risk of HIV infection.
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DOI:
10.1371/journal.pone.0002731
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发表时间:
2008-07-16
期刊:
影响因子:
3.7
通讯作者:
Sullivan, Patrick S.
Sullivan, Patrick S.
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Begley, Elin B.;Jafa, Krishna;Voetsch, Andrew C.;Heffelfinger, James D.;Borkowf, Craig B.;Sullivan, Patrick S.

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包皮环切术可以减少非洲异性恋男性中艾滋病毒的感染,但目前尚不清楚包皮环切术是否可以减少美国男男性行为者 (MSM) 中艾滋病毒的感染率,或者如果建议的话,MSM 是否愿意接受包皮环切术。我们在 2006 年的同性恋骄傲活动中采访了假定 HIV 呈阴性的 MSM。我们向未受割礼的受访者询问了是否愿意接受包皮环切术,如果事实证明包皮环切术可以降低 MSM 中感染 HIV 的风险,并了解包皮环切术的障碍。使用多变量逻辑回归来识别与割礼意愿相关的协变量。在 780 名男男性行为者中,有 133 名 (17%) 未受割礼。其中,71 人(53%)愿意接受割礼。意愿与黑人种族(确切比值比[OR]:3.4,95%置信区间[CI]:1.3-9.8)、非注射药物使用(OR:6.1,95% CI:1.8-23.7)和感知阴茎癌风险降低(OR:4.7,95% CI:2.0-11.9)相关。关于包皮环切术最常见的担忧是术后疼痛和伤口感染。超过一半未受割礼的男男性行为者,尤其是黑人男男性行为者,表示愿意接受割礼。如果在美国建议 MSM 接受包皮环切术,则包皮环切术的风险和益处应成为教育材料的一部分。
Circumcision reduces HIV acquisition among heterosexual men in Africa, but it is unclear if circumcision may reduce HIV acquisition among men who have sex with men (MSM) in the United States, or whether MSM would be willing to be circumcised if recommended. We interviewed presumed-HIV negative MSM at gay pride events in 2006. We asked uncircumcised respondents about willingness to be circumcised if it were proven to reduce risk of HIV among MSM and perceived barriers to circumcision. Multivariate logistic regression was used to identify covariates associated with willingness to be circumcised. Of 780 MSM, 133 (17%) were uncircumcised. Of these, 71 (53%) were willing to be circumcised. Willingness was associated with black race (exact odds ratio [OR]: 3.4, 95% confidence interval [CI]: 1.3–9.8), non-injection drug use (OR: 6.1, 95% CI: 1.8–23.7) and perceived reduced risk of penile cancer (OR: 4.7, 95% CI: 2.0–11.9). The most commonly endorsed concerns about circumcision were post-surgical pain and wound infection. Over half of uncircumcised MSM, especially black MSM, expressed willingness to be circumcised. Perceived risks and benefits of circumcision should be a part of educational materials if circumcision is recommended for MSM in the United States.
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