ASAView: database and tool for solvent accessibility representation in proteins.
ASAView: database and tool for solvent accessibility representation in proteins.
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DOI：
10.1186/1471-2105-5-51
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发表时间：
2004-05-01
影响因子：
3
通讯作者：
Sarai A
中科院分区：
文献类型：
--
作者：
Ahmad S;Gromiha M;Fawareh H;Sarai A
蛋白质中氨基酸的可溶解表面积（阿萨）或溶剂可及性具有重要意义。表面残基的知识有助于定位活性位点的潜在候选者。因此，在二维模型中快速观察表面残基的方法将有助于立即了解蛋白质表面和内核中的氨基酸残基群体。ASAView是一个算法，一个应用程序和蛋白质内氨基酸残基的溶剂可及性的示意图表示数据库。溶剂可及性的特征二维螺旋图提供了残留物暴露表面积的方便图形视图。此外，还提供了条形图形式的连续图。整个蛋白质数据库（PDB）中包含的蛋白质的在线图分别针对整个蛋白质及其链提供。这些溶剂可及性的图形可能提供蛋白质中残基的总体拓扑分布的快速视图。还提供了溶剂可及性的链式计算。
Accessible surface area (ASA) or solvent accessibility of amino acids in a protein has important implications. Knowledge of surface residues helps in locating potential candidates of active sites. Therefore, a method to quickly see the surface residues in a two dimensional model would help to immediately understand the population of amino acid residues on the surface and in the inner core of the proteins. ASAView is an algorithm, an application and a database of schematic representations of solvent accessibility of amino acid residues within proteins. A characteristic two-dimensional spiral plot of solvent accessibility provides a convenient graphical view of residues in terms of their exposed surface areas. In addition, sequential plots in the form of bar charts are also provided. Online plots of the proteins included in the entire Protein Data Bank (PDB), are provided for the entire protein as well as their chains separately. These graphical plots of solvent accessibility are likely to provide a quick view of the overall topological distribution of residues in proteins. Chain-wise computation of solvent accessibility is also provided.
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影响因子：
2.9
作者：
Pollastri, G;Baldi, P;Casadio, R
通讯作者：
Casadio, R
DOI：
10.1093/protein/12.7.549
发表时间：
1999-07-01
期刊：
PROTEIN ENGINEERING
影响因子：
--
作者：
Gromiha, MM;Oobatake, M;Sarai, A
通讯作者：
Sarai, A
影响因子：
14.9
作者：
Laskowski, RA
通讯作者：
Laskowski, RA
影响因子：
5.6
作者：
Gilis, D;Rooman, M
通讯作者：
Rooman, M
影响因子：
5.6
作者：
RICHMOND, TJ;RICHARDS, FM
通讯作者：
RICHARDS, FM