Optimizing Nutritional Status in Patients Undergoing Radical Cystectomy: A Systematic Scoping Review.
Optimizing Nutritional Status in Patients Undergoing Radical Cystectomy: A Systematic Scoping Review.
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DOI：
10.3233/blc-200428
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Hamilton-Reeves J
中科院分区：
文献类型：
--
作者：
Alam SM;Michel C;Robertson H;Camargo JT;Linares B;Holzbeierlein J;Hamilton-Reeves J
对于接受多模式肿瘤干预的患者，营养是一个可改变的风险因素，在膀胱癌的治疗中起着重要的支持作用。对于接受根治性膀胱切除术（RC）的患者，营养不良与术后并发症和死亡率增加有关。本范围审查的目的是描述营养干预对接受RC治疗的膀胱癌患者的作用。根据范围审查的系统性审查首选报告项目扩展（PRISMA-ScR）指南进行了多数据库系统范围审查。先验地开发了检索词，以识别关注接受RC的膀胱癌患者的营养干预的临床试验。符合条件的文章是评价接受RC的成人患者营养干预的临床试验的原始研究文章或摘要。如果文章没有关注营养干预，如果患者没有诊断为膀胱癌，或者如果没有进行RC，则将其排除。文章由作者独立审查，纳入/排除基于共识。共识别出83篇文章，其中17篇被纳入最终分析。摘要筛选期间共排除了49篇文章。基于对全文文献的审查，排除了另外17篇文献。范围审查的结果表明，对接受RC的患者进行营养筛查、评估和干预的数据很少。尽管肠外营养（PN）似乎与RC后更大的并发症相关，但术后早期引入食物或肠内喂养可提供益处，并且侧重于高蛋白饮食的免疫营养素补充剂有可能更好地优化手术结局。虽然接受RC的患者营养不良的患病率和后果是公认的，但评估这一人群营养筛查、评估和干预措施的数据有限。在这一领域进行未来的临床试验至关重要。
Nutrition is a modifiable risk factor for patients undergoing multimodal oncologic interventions and plays a major supportive role in the setting of bladder cancer. For patients undergoing radical cystectomy (RC), malnutrition is associated with increased postoperative complications and mortality. The purpose of this scoping review is to characterize the role of nutritional interventions for patients undergoing RC for bladder cancer. A multi-database systematic scoping review based on the Preferred Reporting Items for Systematic Reviews extension for Scoping Reviews (PRISMA-ScR) guidelines was performed. Search terms were developed a priori to identify clinical trials that focused on nutritional interventions for patients with bladder cancer undergoing RC. Eligible articles were original research articles or abstracts from clinical trials evaluating nutritional interventions in adult patients undergoing RC. Articles were excluded if they did not focus on a nutritional intervention, if patients did not carry a diagnosis of bladder cancer, or if RC was not performed. Articles were reviewed independently by the authors, and inclusion/exclusion were based on consensus agreement. A total of 83 articles were identified, of which 17 were included in the final analysis. A total of 49 articles were excluded during abstract screening. An additional 17 articles were excluded based on the review of full-text articles. Results of the scoping review suggest that data on the use of nutritional screening, assessment, and intervention for patients undergoing RC are scarce. Although parenteral nutrition (PN) appears to be associated with greater complications after RC, early introduction of food postoperatively or feeding enterally offers benefit and immunonutrition supplements with a focus on a high protein diet have the potential to better optimize surgical outcomes. Although the prevalence and consequences of malnutrition among patients undergoing RC are well-established, there are limited data evaluating the use of nutritional screening, assessment, and interventions for this population. The pursuit of future clinical trials in this space is critical.
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影响因子：
--
作者：
Kim TN;Choi KM
通讯作者：
Choi KM
影响因子：
2.1
作者：
Kaye, Deborah R.;Schafer, Christine;Montgomery, Jeffrey S.
通讯作者：
Montgomery, Jeffrey S.
影响因子：
2.4
作者：
Declercq, Peter;De Win, Gunter;Isabel, Spriet
通讯作者：
Isabel, Spriet
影响因子：
4.2
作者：
Karl, A.;Staehler, M.;Rittler, P.
通讯作者：
Rittler, P.
影响因子：
9
作者：
ASKANAZI, J;HENSLE, TW;KINNEY, JM
通讯作者：
KINNEY, JM