Changes in the pattern of infection caused by Streptococcus pyogenes
Changes in the pattern of infection caused by Streptococcus pyogenes
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化脓性链球菌引起的感染模式的变化
DOI：
10.1017/s095026880006739x
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发表时间：
1988
影响因子：
4.2
通讯作者：
G. Colman
中科院分区：
文献类型：
--
作者：
E. Gaworzewska;G. Colman
在送往参比实验室的12469株化脓性链球菌培养物中测定了t蛋白和m蛋白抗原的分布。其中7232例（58%）来自医院患者，249例（2%）来自医院工作人员，4988例（40%）来自社区。调查从1980年1月持续到1987年6月。在此期间，m - 6型、49型和81型的分离株数量先上升后下降，被1型、3型和28型所取代。m - 4型和m - 12型分离株所占比例保持不变。从肾炎或风湿热病例中获得的菌株很少，但从严重感染和死亡病例中获得的菌株数量有所增加。自1985年以来收到的55株（80%）致命感染中有44株属于m - 1型。在那些年里，除两种致命感染外，其他所有菌株都属于m - 3型。m - 1型的代表也与冻疮有关。3型和4型主要来自猩红热，1型、4型、12型和49型主要来自肾炎，49型和81型主要来自肉类工人的皮肤感染，28型主要来自产褥期败血症。M型率为97%，但在引起脓皮病的菌株中，新的M抗原有待确定。
SUMMARY The distribution of T-and M-protein antigens was determined in 12469 cultures of Streptococcus pyogenes sent to a reference laboratory. Of these 7232 (58%) were isolates from hospital patients, 249 (2%) from hospital staff and 4988 (40%) from the community. The survey extended from January 1980 to June 1987. During this timo the numbers of isolates of M-types 6, 49 and 81 rose then fell, being replaced by types 1, 3 and 28. The proportion of isolates of M-types 4 and 12 remained constant. Few strains were received from cases of nephritis or rheumatic fever but there has been an increase in the number of strains from serious infections and deaths. Forty-four of the 55 (80%) strains received since 1985 from fatal infections have belonged to M-type 1. All other strains, bar two, received from fatal infections in those years belonged to M-type 3. Representatives of M-type 1 were also associated with crysipelas. Types 3 and 4 predominated among the isolates from scarlet fever, types 1, 4, 12 and 49 from nephritis, types 49 and 81 from skin infections in meat workers and type 28 in cases of puerperal sepsis. The M-typability rate was 97% but new M antigens await definition among strains causing pyoderma.
灭活流感疫苗临床试验总结 - 1978 年。
DOI：
10.1093/clinids/5.4.723
发表时间：
1983
期刊：
Reviews of infectious diseases
影响因子：
--
作者：
LaMontagne,JR;Noble,GR;Quinnan,GV;Curlin,GT;Blackwelder,WC;Smith,JI;Ennis,FA;Bozeman,FM
通讯作者：
Bozeman,FM
影响因子：
158.5
作者：
CONE, LA;WOODARD, DR;TOMORY, GS
通讯作者：
TOMORY, GS