Diagnostic accuracy of mammography, ultrasonography and magnetic resonance imaging in the detection of intraductal spread of breast cancer following neoadjuvant chemotherapy.
Diagnostic accuracy of mammography, ultrasonography and magnetic resonance imaging in the detection of intraductal spread of breast cancer following neoadjuvant chemotherapy.
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乳房X光检查、超声检查和磁共振成像在检测新辅助化疗后乳腺癌导管内扩散方面的诊断准确性。
DOI：
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发表时间：
2007
期刊：
影响因子：
--
通讯作者：
Yohsuke Tanaka
中科院分区：
文献类型：
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作者：
K. Kubota;Y. Ogawa;A. Nishioka;S. Kariya;S. Itoh;Y. Murata;N. Hamada;H. Maeda;Yohsuke Tanaka
本研究的目的是评估乳房x光检查、超声检查和增强磁共振成像在术前新辅助化疗后乳腺癌导管内扩散诊断中的准确性。在新辅助化疗前后，我们对连续42例女性乳腺癌患者的肿块外正常乳腺组织共168个区域进行了评估。新辅助化疗包括2 - 4个周期的以阿霉素为基础的CAF方案。多因素分析显示，新辅助化疗前乳腺x线片钙化和超声低回声结构的大小与病理研究显示导管内扩散相关。我们的研究表明，乳房x光检查和超声检查有助于避免保守乳房手术后因导管内扩散引起的残留癌细胞。
The purpose of this study is to evaluate the accuracy of mammography, ultrasonography, and contrast-enhanced magnetic resonance imaging for the diagnosis of intraductal spread of breast cancer following preoperative neoadjuvant chemotherapy. We evaluated a total of 168 areas of normal breast tissue outside the mass in 42 consecutive female patients with breast cancer using each imaging modality both before and after neoadjuvant chemotherapy. Neoadjuvant chemotherapy comprised two to four cycles of adriamycin-based CAF regimen. Multivariate analysis indicated that calcification on mammography and size of hypoechoic structures on ultrasonography prior to neoadjuvant chemotherapy shows a correlation with intraductal spread on pathologic study. Our study reveals that mammography and ultrasonography are useful in avoiding residual cancer cells caused by intraductal spread following conservative breast surgery.
DOI：
10.1093/oxfordjournals.jncimonographs.a003469
发表时间：
2001-12
期刊：
Journal of the National Cancer Institute. Monographs
影响因子：
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作者：
N. Wolmark;Jiping Wang;E. Mamounas;J. Bryant;B. Fisher
通讯作者：
N. Wolmark;Jiping Wang;E. Mamounas;J. Bryant;B. Fisher
影响因子：
158.5
作者：
Fisher, B;Anderson, S;Wolmark, N
通讯作者：
Wolmark, N