The headache registry of the German Migraine and Headache Society (DMKG): baseline data of the first 1,351 patients.
The headache registry of the German Migraine and Headache Society (DMKG): baseline data of the first 1,351 patients.
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DOI：
10.1186/s10194-022-01447-3
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发表时间：
2022-07-01
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尽管许多头痛疾病都有很好的治疗选择，但并不是所有的患者都能受益，残疾程度仍然很高。为了设计改善头痛护理的策略，观察标准护理的真实数据是必要的。因此，德国偏头痛协会(DMKG)建立了DMKG头痛登记处。在这里，我们介绍方法和基线数据。经认可的德国头痛中心(诊所或私人诊所)可以为他们的患者提供参与。患者在预约医生之前提供头痛病史、当前头痛负荷(包括流动头痛日记)、用药情况和合并症，并回答有效问卷。医生使用这些数据作为他们病历记录的基础，并添加、更改或确认一些核心信息。在下一次就诊之前，患者被要求更新他们的数据。在接下来的几年里，患者将继续纳入其中。目前的分析基于第一次就诊完成的1,351名患者(女性1,110人，平均年龄39.6 ± 12.9年)。大多数参与者都被诊断为偏头痛。参与者每月头痛天数为14.4 ± 8.5天，急性用药天数为7.7 ± 6.1天，63.9%的患者偏头痛残疾评估(MIDAS)等级为4级(重度残疾)。93.6%的患者使用至少一种急性头痛药物，最常见的是曲普坦(60.0%)或非阿片类止痛药(58.3%)。45.0%的人至少使用一种头痛预防药物，最常见的是抗抑郁药(11.4%，主要是阿米替林8.4%)或CGRP(受体)抗体(9.8%)。停止预防性用药最常见的原因是无效(54.2%)和副作用(43.3%)。DMKG头痛登记处允许以横断面和纵向方法持续监控德国头痛中心的头痛护理。DMKG头痛注册登记在德国临床试验登记(DRKS 00021081)。
Although good treatment options exist for many headache disorders, not all patients benefit and disability continues to be large. To design strategies for improving headache care, real-world data observing standard care is necessary. Therefore, the German Migraine and Headache Society (DMKG) has established the DMKG Headache Registry. Here we present methods and baseline data. Accredited German headache centers (clinic-based or private practice) can offer participation to their patients. Patients provide headache history, current headache load (including a mobile headache diary), medication and comorbidities and answer validated questionnaires, prior to their physician appointment. Physicians use these data as the base of their history taking, and add, change or confirm some central information. Before the next visit, patients are asked to update their data. Patients will continuously be included over the next years. The present analysis is based on the first 1,351 patients (1110 females, 39.6 ± 12.9 years) with a completed first visit. Most participants had a migraine diagnosis. Participants had 14.4 ± 8.5 headache days and 7.7 ± 6.1 acute medication days per month and 63.9% had a migraine disability assessment (MIDAS) grade 4 (severe disability). 93.6% used at least one acute headache medication, most frequently a triptan (60.0%) or non-opioid analgesic (58.3%). 45.0% used at least one headache preventive medication, most frequently an antidepressant (11.4%, mostly amitriptyline 8.4%) or a CGRP(receptor) antibody (9.8%). Most common causes for discontinuation of preventive medication were lack of effect (54.2%) and side effects (43.3%). The DMKG Headache Registry allows to continuously monitor headache care at German headache centers in both a cross-sectional and a longitudinal approach. The DMKG Headache Registry is registered with the German Clinical Trials Register (DRKS 00021081).
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影响因子：
5
作者：
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