Coagulopathies in novel coronavirus (SARS-CoV-2) pandemic: Emerging evidence for hematologists.
Coagulopathies in novel coronavirus (SARS-CoV-2) pandemic: Emerging evidence for hematologists.
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DOI：
10.1016/j.sjbs.2020.11.006
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发表时间：
2021-01
影响因子：
4.4
通讯作者：
Al-Subaie AM
中科院分区：
文献类型：
--
作者：
Al-Subaie AM
冠状病毒病（COVID-19）也称为急性呼吸综合征冠状病毒-2（SARS-CoV2），是一种传染性疾病，其表型从无症状到急性呼吸窘迫综合征（ARDS）或多器官功能障碍综合征（MODS），在某些病例中最终会导致死亡。这些患者经常报告出现凝血障碍，但其发病机制仍不完全清楚。所提出的这些凝血病的机制包括血管中具有微血栓和/或大血栓形成的高凝状态。据报告或提出，COVID-19 患者的循环促血栓因子发生了许多变化，包括因子 VIII 和纤维蛋白原升高、循环促血栓微粒和高粘滞血症。 COVID-19 患者表现出多种凝血病，并且静脉血栓栓塞 (VTE) 的风险很高，需要早期干预。本文回顾了有关 COVID-19 患者凝血病评估和管理的不断变化的数据。
The coronavirus disease (COVID-19), which is also known as acute respiratory syndrome coronavirus-2 (SARS-CoV2) is a transmissible disease, has phenotypes varying from asymptomatic to Acute Respiratory Distress Syndrome (ARDS) or multiple organ dysfunction syndrome (MODS) and ultimately death in certain cases. Coagulation disorders are being frequently reported amongst these patients and the pathogenesis is still not completely understood. Proposed mechanisms for these coagulopathies comprise a hypercoagulable state with micro- and/or macro-thrombosis in the vessels. A number of changes have been reported or proposed in circulating prothrombotic factors in COVID-19 patients and includes elevation in both factor VIII and fibrinogen, circulating prothrombotic microparticles and hyperviscosity. The COVID-19 patients are showing varied coagulopathies and are at high risk for venous thromboembolism (VTE) which demands an early intervention. This paper reviews the evolving data regarding the evaluation and managing of coagulopathies in patients with COVID-19.
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影响因子：
7.7
作者：
van de Veerdonk, Frank L.;Netea, Mihai G.;van der Hoeven, Hans
通讯作者：
van der Hoeven, Hans
影响因子：
168.9
作者：
Huang, Chaolin;Wang, Yeming;Cao, Bin
通讯作者：
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影响因子：
10.4
作者：
Cui, Songping;Chen, Shuo;Wang, Feng
通讯作者：
Wang, Feng
DOI：
10.1111/jth.14854
发表时间：
2020-07
期刊：
Journal of thrombosis and haemostasis : JTH
影响因子：
--
作者：
通讯作者：
--
影响因子：
10.4
作者：
Tang, Ning;Li, Dengju;Sun, Ziyong
通讯作者：
Sun, Ziyong