Body image distortion reveals amygdala activation in patients with anorexia nervosa – a functional magnetic resonance imaging study
Body image distortion reveals amygdala activation in patients with anorexia nervosa – a functional magnetic resonance imaging study
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身体图像扭曲揭示神经性厌食症患者杏仁核激活——一项功能性磁共振成像研究
DOI：
10.1016/s0304-3940(02)00312-9
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发表时间：
2002
影响因子：
2.5
通讯作者：
Martin H. Schmidt
中科院分区：
文献类型：
--
作者：
G. Seeger;D. Braus;M. Ruf;U. Goldberger;Martin H. Schmidt
在神经性厌食症患者中，身体形象扭曲是一个核心且经常持续的症状，即使在体重恢复后仍有复发的风险。我们使用功能性磁共振成像（fMRI）结合基于计算机的生活图像失真技术，用女性厌食症患者和健康对照者各自扭曲的身体图像的数字图片进行刺激。在厌食症患者中，对自己身体形象的刺激与右侧杏仁核、右侧梭状回和脑干区域的激活有关。我们的初步研究结果表明，大脑的“恐惧网络”被激活，并强调需要使用功能磁共振成像设计来检查厌食症患者的身体图像扭曲，以进一步纵向评估这种干扰的过程。
In anorexia nervosa patients, body image distortion is a core and often persistent symptom, which continues to pose a risk for relapse even after weight recovery. Using functional magnetic resonance imaging (fMRI) in combination with a computer-based life image distortion technique, we stimulated female anorectic patients and healthy controls with digital pictures of their own body image, individually distorted by themselves. In anorectic patients, stimulation with their own body image was associated with activation in the right amygdala, the right gyrus fusiformis and the brainstem region. Our preliminary findings indicate an activation of the brain's ‘fear network’ and underscore the need for examination of body image distortions in anorectic patients with a fMRI design to further evaluate the course of this disturbance in a longitudinal approach.
影响因子：
3.7
作者：
Lang, PJ;Bradley, MM;Nangia, V
通讯作者：
Nangia, V