MMPs and TIMPs

MMPs and TIMPs
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MMP 和 TIMP

DOI:
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发表时间:
2001
期刊:
影响因子:
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通讯作者:
J. Woessner
J. Woessner
中科院分区:
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文献类型:
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作者:
J. Woessner

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目前已知的脊椎动物基质金属蛋白酶(MMPs)有25种,金属蛋白酶组织抑制物(TIMPs)有4种。本文从历史的角度回顾了这些酶,包括谁发现了每一种蛋白质,序列建立的时间,对蛋白质底物的作用时间,以及使用了什么名称。对于TIMP也采取了类似的方法,并强调了它们除了抑制蛋白酶之外的多种功能。还讨论了来自无脊椎动物、植物和细菌的MMPs。这篇综述是对最初发表在《基质金属蛋白酶协议》第1-23页的同名章节的发展和更新,由I.M.Clark编辑,Humana出版社于2001年出版。
There are currently 25 known vertebrate matrix metalloproteinases (MMPs) and 4 tissue inhibitors of metalloproteinases (TIMPs). This article reviews these proteases from an historical perspective in terms of who discovered each protein, when the sequence was established, when action on protein substrates was demonstrated, and what names have been used. A similar approach is taken for the TIMPS, and their multiple functions in addition to protease inhibition are emphasized. MMPs from invertebrates, plants, and bacteria are also discussed. This review is an outgrowth and update of a chapter by the same name originally published in Matrix Metalloproteinase Protocols, pp. 1–23, edited by I. M. Clark and published by Humana Press in 2001.
牛主动脉内皮细胞分泌的两种相关但不同的金属蛋白酶抑制剂的纯化和表征。
DOI: --
发表时间: 1989
期刊: The Journal of biological chemistry
影响因子: --
作者:
DeClerck,YA;Yean,TD;Ratzkin,BJ;Lu,HS;Langley,KE
通讯作者: Langley,KE
DOI: --
发表时间: 1990
期刊: The Journal of biological chemistry
影响因子: --
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影响因子: --
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期刊: The Journal of biological chemistry
影响因子: --
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