Life course pathways to adult‐onset diabetes

Life course pathways to adult‐onset diabetes
复制标题

成人发病糖尿病的生命历程路径

DOI:
10.1080/19485565.2005.9989104
复制
发表时间:
2005
期刊:
Social Biology
影响因子:
--
通讯作者:
Mira Hidajat
Mira Hidajat
中科院分区:
--
文献类型:
--
作者:
Latrica E. Best;M. Hayward;Mira Hidajat

文献摘要

参考文献

相似文献

早期生活条件,如社会经济地位(SES)和健康,有可能启动多种强化途径,塑造老年人糖尿病的患病率和发病率。使用健康与退休研究(1998-2002)中51岁及以上人群的数据,我们调查了1998年早期生活状况与糖尿病患病率之间的核心中介机制,并在4年的随访期内发病,重点关注成人成就过程和肥胖作为关键机制。我们发现,父亲的教育程度与老年男性和女性的糖尿病患病率呈负相关。然而,没有早期生活SES的标志物与老年男性和女性的糖尿病发病直接相关,成年SES对糖尿病发病的负面影响只涉及女性。早期健康状况影响女性糖尿病的发病,但不影响患病率,在男性中没有发现这种关联的证据。我们没有发现任何证据表明肥胖是一个重要的机制连接无论是早期生活或成年SES与糖尿病的发展,在男性或女性。我们推测,早期生活SES可能会加速糖尿病在年轻时的发展,并且连接生命过程SES,早期生活健康和糖尿病的途径部分具有性别特异性和生物学性质。
Abstract Early life conditions, such as socioeconomic status (SES) and health, have the potential to set in motion multiple and reinforcing pathways that shape both the prevalence and onset of diabetes among older adults. Using data from the Health and Retirement Study (1998–2002) for persons age 51 years and older, we investigated the core mediating mechanisms linking early life conditions with diabetes prevalence in 1998 and onset over a 4‐year follow‐up period, focusing on adult achievement processes and obesity as key mechanisms. We found that father's education is negatively associated with diabetes prevalence for older men and women. However, no markers of early life SES are directly associated with older men's and women's onset of diabetes, and the negative effects of adult SES on diabetes onset pertain only to women. Early life health affects the onset of diabetes among women—but not the prevalence—and no evidence of this association was found for men. We found no evidence that obesity is an important mechanism connecting either early life or adult SES with diabetes development in men or women. We speculate that early life SES may accelerate the development of diabetes at younger ages, and that the pathways linking life course SES, early life health, and diabetes are partly gender‐specific and biological in nature.
DOI: 10.1001/jama.287.19.2534
发表时间: 2002-05-15
影响因子: 120.7
作者:
Innes, KE;Byers, TE;Hamman, RF
通讯作者: Hamman, RF
健康方面的社会不平等解开了根本机制。
DOI: --
发表时间: 2001
期刊: Annals of the New York Academy of Sciences.
影响因子: --
作者:
Goldman,N
通讯作者: Goldman,N
DOI: 10.1001/archinte.160.14.2117
发表时间: 2000-07-24
影响因子: --
作者:
Folsom, AR;Kushi, LH;Prineas, R
通讯作者: Prineas, R
DOI: 10.2105/ajph.82.6.816
发表时间: 1992-06-01
影响因子: 12.7
作者:
WINKLEBY, MA;JATULIS, DE;FORTMANN, SP
通讯作者: FORTMANN, SP
DOI: 10.1001/jama.280.4.356
发表时间: 1998-07-22
影响因子: 120.7
作者:
Winkleby, MA;Kraemer, HC;Varady, AN
通讯作者: Varady, AN