A photoacoustic microscopy system using MEMS and fibre tip transducers for all-optical control

A photoacoustic microscopy system using MEMS and fibre tip transducers for all-optical control
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使用 MEMS 和光纤尖端传感器进行全光学控制的光声显微镜系统

DOI:
10.1117/12.2609765
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发表时间:
2022
期刊:
--
影响因子:
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通讯作者:
Donnachie M
Donnachie M
中科院分区:
--
文献类型:
--
作者:
Donnachie M

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介绍了一种三维光声显微镜系统,该系统采用光学MEMS和光纤探头作为有源元件,实现全光定位和读出。使用静电致动的2轴MEMS扫描仪控制激发光束位置。这允许快速3D扫描而没有由载物台扫描引起的运动诱导伪影,以及感兴趣区域的选择性成像。一个20 MHz的光纤尖端传感器用于声学检测,这允许使用各种样品架,包括常见的方法,如多孔板和培养皿。
A 3D photoacoustic microscopy (PAM) system is presented and characterized, using optical MEMS and fibre tip transducers as active elements to provide all-optical positioning and read-out. The excitation beam position is controlled using an electrostatically actuated 2-axis MEMS scanner. This allows for fast 3D scanning without motion-induced artefacts caused by stage scanning, and selective imaging of regions of interest. A 20 MHz fibre tip transducer is used for acoustic detection, which allows a variety of sample holders to be used including common approaches such as multi-well plates and petri-dishes.
DOI: 10.1016/j.cobme.2017.09.004
发表时间: 2017-12
影响因子: 3.9
作者:
Miller DR;Jarrett JW;Hassan AM;Dunn AK
通讯作者: Dunn AK