Revisiting the Daily Timing of POS Phagocytosis.
Revisiting the Daily Timing of POS Phagocytosis.
复制标题
重新审视 POS 吞噬作用的每日计时。
DOI:
10.1007/978-3-031-27681-1_75
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发表时间:
2023
影响因子:
--
通讯作者:
Williams,DavidS
中科院分区:
文献类型:
--
作者:
Paniagua,AntonioE;Sabharwal,HarjasS;Kethu,Kausalya;Chang,AndrewW;Williams,DavidS
Retinal pigment epithelium (RPE) cells daily ingest the tips of the photoreceptor outer segments (POSs), with phagosome number varying throughout a 24-h cycle. A major focus in the literature has been on a peak in phagosome concentration shortly after lights-on. Moreover, this peak has frequently been inferred to represent a peak in POS tip ingestion. Here, we have reviewed old and new literature on the daily cycle of phagosome number in the RPE and conclude that there is more variation in the timing of phagosome concentration peaks than is currently acknowledged. We also discuss that phagosome quantity is affected by the rate of phagosome degradation as well as the rate of ingestion; given that phagosome half-life may not be constant throughout the daily cycle, maximal POS ingestion may not necessarily coincide with a peak in phagosome concentration.
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影响因子:
2.9
作者:
E. Young;H. Akil
通讯作者:
H. Akil
DOI:
--
发表时间:
1959
期刊:
Journal of Physiology
影响因子:
--
作者:
G. Rochefort;J. Rosenberger;M. Saffran
通讯作者:
M. Saffran
影响因子:
3.1
作者:
A. Daniels;A. Goodwin;L. Keil;J. Vernikos‐Danellis
通讯作者:
J. Vernikos‐Danellis
影响因子:
1.9
作者:
FANSELOW, MS
通讯作者:
FANSELOW, MS
DOI:
10.1507/endocrj1954.32.709
发表时间:
1985
期刊:
Endocrinologia japonica
影响因子:
--
作者:
S. Suemaru;K. Hashimoto;Z. Ota
通讯作者:
Z. Ota