The preventive health behaviors of long-term survivors of cancer and hematopoietic stem cell transplantation compared with matched controls.

The preventive health behaviors of long-term survivors of cancer and hematopoietic stem cell transplantation compared with matched controls.
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DOI:
10.1016/j.bbmt.2009.09.015
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发表时间:
2010-02
影响因子:
4.3
通讯作者:
Wingard, John R.
Wingard, John R.
中科院分区:
医学2区
文献类型:
--
作者:
Bishop, Michelle M.;Lee, Stephanie J.;Beaumont, Jennifer L.;Andrykowski, Michael A.;Rizzo, J. Douglas;Sobocinski, Kathleen A.;Wingard, John R.

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目前对造血细胞移植(HCT)治疗的癌症幸存者的健康促进,预防和疾病筛查行为知之甚少,这些癌症幸存者接受了艰苦的治疗,并且可能具有晚期效应和继发性恶性肿瘤的特殊风险。本研究的目的是检查目前的健康和二级预防行为的长期HCT幸存者相比,非癌症匹配的控制,并确定社会人口和临床因素与适当的预防措施。HCT存活者(n=662)来自40个北美移植中心。同行提名的熟人的幸存者匹配的性别,年龄,教育和婚姻状况,作为对照组(n=158)。在HCT后平均6.7年(范围1.8 - 22.6年)收集数据。尽管体格检查的频率更高,但HCT幸存者的健康状况和筛查行为与匹配的对照组相似。社会人口学因素与健康预防行为的预期方式。发现疾病组和移植类型之间存在一些差异,急性白血病幸存者报告定期运动的可能性较小,自体移植幸存者比同种异体移植幸存者更有可能报告乳腺癌和宫颈癌筛查,而同种异体幸存者比自体移植幸存者更有可能报告皮肤检查。尽管与卫生保健提供者的接触程度较高,但HCT幸存者的健康行为与匹配的对照组没有什么不同,与非HCT癌症幸存者报告的健康行为相当。仍有相当大的改进余地。这些发现支持HCT幸存者和卫生从业人员需要进一步教育。
Little is known about the health promotion, prevention, and disease screening behaviors of cancer survivors treated with hematopoietic cell transplantation (HCT), who undergo arduous treatment and may be at particular risk for late effects and secondary malignancies. The purpose of this study was to examine the current health and secondary prevention behaviors of long-term HCT survivors compared to noncancer matched controls and to identify sociodemographic and clinical factors associated with appropriate prevention practices. HCT survivors (n=662) were drawn from 40 North American transplant centers. Peer-nominated acquaintances of survivors matched on sex, age, education, and marital status, served as controls (n=158). Data were collected a mean of 6.7 years post-HCT (range 1.8 – 22.6 years). Despite greater frequency of physical exams, HCT survivor health and screening behaviors were similar to matched controls. Sociodemographic factors were associated with health prevention behaviors in expected ways. Some differences between disease group and type of transplant were found, with survivors of acute leukemia less likely to report regular exercise, autologous transplant survivors more likely than allogeneic to report screenings for breast and cervical cancer, and allogeneic survivors more likely than autologous to report a skin exam in the last year. Despite higher levels of engagement with health care providers, HCT survivor health behaviors were no different than matched controls and comparable to those reported by non HCT cancer survivors. There remains considerable room for improvement. These findings support the need for further education of both HCT survivors and health practitioners.
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