Prefrontal Cortex Involvement during Dual-Task Stair Climbing in Healthy Older Adults: An fNIRS Study.
Prefrontal Cortex Involvement during Dual-Task Stair Climbing in Healthy Older Adults: An fNIRS Study.
复制标题
DOI：
10.3390/brainsci11010071
复制
发表时间：
2021-01-07
期刊：
影响因子：
3.3
通讯作者：
Fraser S
中科院分区：
文献类型：
--
作者：
Salzman T;Aboualmagd A;Badawi H;Tobón-Vallejo D;Kim H;Dahroug L;Laamarti F;El Saddik A;Fraser S
随着年龄的增长，执行功能和运动控制缺陷会对步态表现产生不利影响，但在爬楼梯过程中这种相互作用的神经相关性仍不清楚。20名老年人（72.7 ± 6.9岁）完成了单一任务：站立和响应响应时间任务（SC），上楼梯或下楼梯（SMup，SMdown）;以及双重任务：在上楼梯或下楼梯时响应（DTup，DTdown）。采用功能性近红外光谱仪（fNIRS）检测前额叶血流动力学反应变化（HbO 2、HbR），采用鞋内智能鞋垫测量步态速度，记录发声反应时间和准确性。结果显示，双任务与单任务相比，HbO 2增加（p = 0.020），反应时间较慢（p < 0.001）。不同任务或爬楼梯条件下的HbR（p = 0.549）、准确性（p = 0.135）和步态速度（p = 0.475）无显著差异。HbO 2和反应时间的研究结果表明，执行过程中的效率较低的双重任务。这些发现，除了步态速度和准确性的维持，可以提供洞察神经变化之前的性能下降。为了捕捉爬楼梯和爬楼梯之间的微妙差异，并扩展我们对老年人爬楼梯的神经相关性的理解，未来的研究应该研究更困难的认知任务。
Executive function and motor control deficits adversely affect gait performance with age, but the neural correlates underlying this interaction during stair climbing remains unclear. Twenty older adults (72.7 ± 6.9 years) completed single tasks: standing and responding to a response time task (SC), ascending or descending stairs (SMup, SMdown); and a dual-task: responding while ascending or descending stairs (DTup, DTdown). Prefrontal hemodynamic response changes (∆HbO2, ∆HbR) were examined using functional near-infrared spectroscopy (fNIRS), gait speed was measured using in-shoe smart insoles, and vocal response time and accuracy were recorded. Findings revealed increased ∆HbO2 (p = 0.020) and slower response times (p < 0.001) during dual- versus single tasks. ∆HbR (p = 0.549), accuracy (p = 0.135) and gait speed (p = 0.475) were not significantly different between tasks or stair climbing conditions. ∆HbO2 and response time findings suggest that executive processes are less efficient during dual-tasks. These findings, in addition to gait speed and accuracy maintenance, may provide insights into the neural changes that precede performance declines. To capture the subtle differences between stair ascent and descent and extend our understanding of the neural correlates of stair climbing in older adults, future studies should examine more difficult cognitive tasks.
登录
查看更多内容
影响因子：
4.8
作者：
Fraser, Sarah A.;Dupuy, Olivier;Bherer, Louis
通讯作者：
Bherer, Louis
影响因子：
3.1
作者：
Beurskens R;Bock O
通讯作者：
Bock O
影响因子：
6.7
作者：
Delbaere, Kim;Close, Jacqueline C. T.;Lord, Stephen R.
通讯作者：
Lord, Stephen R.
影响因子：
5.6
作者：
Holtzer, Roee;Kraut, Rebecca;Ye, Kenny
通讯作者：
Ye, Kenny
影响因子：
1.8
作者：
Lajoie, Y;Teasdale, N;Fleury, M
通讯作者：
Fleury, M