Frequencies of chromosomal inversions in Drosophila melanogaster in Fukushima after the nuclear power plant accident.
Frequencies of chromosomal inversions in Drosophila melanogaster in Fukushima after the nuclear power plant accident.
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DOI：
10.1371/journal.pone.0192096
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Inoue Y
中科院分区：
文献类型：
--
作者：
Itoh M;Kajihara R;Kato Y;Takano-Shimizu T;Inoue Y
为了调查2011年福岛第一核电站事故释放的大量放射性核素的遗传影响，我们对2012年和2013年在福岛3个地点收集的2,304个黑腹果蝇单倍体基因组进行了染色体倒位调查。2012年，在298个基因组中没有发现独特的倒位，2013年，在2,006个基因组中只有两个。观测到的频率甚至低于日本独特逆温的长期平均频率。2012年，还在福岛、京都和西表（冲绳）检查了常见的世界性反转。在福岛的3个样品中，环境辐射水平最高的饭坂地区的蝇类的In（2L）t频率最低，而In（3R）P频率最高，这与高污染地区蝇类的频率降低的预期相反。这些结果表明，在这个水平的遗传分析，福岛种群的D。黑腹动物在放射性核素释放后不会受到负面影响。转座P-元件迁移率不太可能单独或协同放射性诱导DNA损伤，因为它们的转座活性在福岛菌株中被完全抑制。然而，应当指出的是，由于进入禁区受到限制，我们只能对放射性污染相对较低（0.39-0.63 μSv/h）地区的人口进行采样。因此，目前的研究可能不足以检测在严重污染地区可能产生的任何影响。
In order to investigate genetic impact of a large amount of radionuclides released by the Fukushima Dai-ichi Nuclear Power Plant accident in 2011, we surveyed 2,304 haploid genomes of Drosophila melanogaster collected in three localities in Fukushima in 2012 and 2013 for chromosomal inversions. No unique inversion was found in 298 genomes in 2012 and only two in 2,006 genomes in 2013. The observed frequencies were even lower than the long-term average frequency of unique inversions in Japan. The common cosmopolitan inversions were also examined in Fukushima, Kyoto, and Iriomote (Okinawa) in 2012. Among three samples in Fukushima, the flies in Iizaka, where environmental radiation level was the highest, showed the lowest frequency of In(2L)t, but the highest frequency of In(3R)P, contrary to the expectation of decreasing of their frequencies in higher polluted areas. These results suggest that, at this level of genetic analysis, Fukushima populations of D. melanogaster would not have been negatively impacted following the release of radionuclides. Transposable P-element mobility was not likely to induce DNA damage solely or synergistically with radioactivity, because their transposition activity was totally repressed in the Fukushima strains. However, it should be noted that, because of limitations in access to the exclusion zone, we could only sample the populations in areas of relatively low radioactive contamination (0.39–0.63 μSv/h). Therefore, the present study is likely to be underpowered to detect any effects that might be expected in heavily contaminated areas.
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影响因子：
4.6
作者：
Hiyama, Atsuki;Nohara, Chiyo;Kinjo, Seira;Taira, Wataru;Gima, Shinichi;Tanahara, Akira;Otaki, Joji M.
通讯作者：
Otaki, Joji M.
DOI：
10.1266/jjg.54.69
发表时间：
1979-01-01
期刊：
JAPANESE JOURNAL OF GENETICS
影响因子：
--
作者：
INOUE, Y;WATANABE, TK
通讯作者：
WATANABE, TK
DOI：
10.1073/pnas.82.16.5418
发表时间：
1985-01-01
影响因子：
11.1
作者：
ANXOLABEHERE, D;NOUAUD, D;TCHEN, P
通讯作者：
TCHEN, P
DOI：
10.1016/0027-5107(87)90309-5
发表时间：
1987-08-01
期刊：
MUTATION RESEARCH
影响因子：
--
作者：
MARGULIES, L;BRISCOE, DI;WALLACE, SS
通讯作者：
WALLACE, SS
影响因子：
3.3
作者：
Corbett-Detig, Russell B.;Cardeno, Charis;Langley, Charles H.
通讯作者：
Langley, Charles H.