Expression of outer surface proteins A and C of Borrelia burgdorferi in Ixodes ricinus

Expression of outer surface proteins A and C of Borrelia burgdorferi in Ixodes ricinus
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伯氏疏螺旋体外表面蛋白A和C在蓖麻硬蜱中的表达

DOI:
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发表时间:
1995
影响因子:
9.4
通讯作者:
B. Wilske
B. Wilske
中科院分区:
医学2区
文献类型:
--
作者:
V. Fingerle;U. Hauser;G. Liegl;B. Peťko;V. Preac‐Mursic;B. Wilske

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A total of 472 field-collected Ixodes ricinus ticks from southern Germany were investigated by immunofluorescence for the presence of Borrelia burgdorferi with a polyvalent rabbit immune serum and with monoclonal antibodies specific for outer surface proteins A and C (OspA and OspC, respectively). Borreliae were detected in 90 ticks with the polyvalent immunofluorescence assay. Infection rates in adults (females, 20.2%; males, 25.2%) were significantly higher than in nymphs (12.1%). OspA was detected in 77 ticks and OspC was detected in only 1 tick with the respective monoclonal antibodies. We therefore conclude that B. burgdorferi in unfed I. ricinus ticks usually expresses OspA and very rarely OspC.
疏螺旋体属表面蛋白的抗原变异。
DOI: 10.1093/cid/10.supplement_2.s399
发表时间: 1988
期刊: Reviews of infectious diseases
影响因子: --
作者:
Barbour,AG
通讯作者: Barbour,AG