CMV and Immunosenescence: from basics to clinics.
CMV and Immunosenescence: from basics to clinics.
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DOI:
10.1186/1742-4933-9-23
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发表时间:
2012-10-31
期刊:
影响因子:
--
通讯作者:
Pawelec G
中科院分区:
文献类型:
--
作者:
Solana R;Tarazona R;Aiello AE;Akbar AN;Appay V;Beswick M;Bosch JA;Campos C;Cantisán S;Cicin-Sain L;Derhovanessian E;Ferrando-Martínez S;Frasca D;Fulöp T;Govind S;Grubeck-Loebenstein B;Hill A;Hurme M;Kern F;Larbi A;López-Botet M;Maier AB;McElhaney JE;Moss P;Naumova E;Nikolich-Zugich J;Pera A;Rector JL;Riddell N;Sanchez-Correa B;Sansoni P;Sauce D;van Lier R;Wang GC;Wills MR;Zieliński M;Pawelec G
Alone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers and proportions of peripheral immune cells in infected-vs-uninfected people. Because the rate of CMV infection increases with age in most countries, it has been suggested that it drives or at least exacerbates “immunosenescence”. This contention remains controversial and was the primary subject of the Third International Workshop on CMV & Immunosenescence which was held in Cordoba, Spain, 15-16th March, 2012. Discussions focused on several main themes including the effects of CMV on adaptive immunity and immunosenescence, characterization of CMV-specific T cells, impact of CMV infection and ageing on innate immunity, and finally, most important, the clinical implications of immunosenescence and CMV infection. Here we summarize the major findings of this workshop.
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影响因子:
3.7
作者:
Larsen M;Sauce D;Arnaud L;Fastenackels S;Appay V;Gorochov G
通讯作者:
Gorochov G
影响因子:
3.9
作者:
Qin, OY;Wagner, WM;Pawelec, G
通讯作者:
Pawelec, G
影响因子:
--
作者:
Derhovanessian, Evelyna;Maier, Andrea B.;Haehnel, Karin;Zelba, Henning;de Craen, Anton J. M.;Roelofs, Helene;Slagboom, Eline P.;Westendorp, Rudi G. J.;Pawelec, Graham
通讯作者:
Pawelec, Graham
影响因子:
4.2
作者:
Dowd, J. B.;Aiello, A. E.;Alley, D. E.
通讯作者:
Alley, D. E.
影响因子:
5.4
作者:
Lachmann, Raskit;Bajwa, Martha;Kern, Florian
通讯作者:
Kern, Florian