The Jpred 3 secondary structure prediction server.
The Jpred 3 secondary structure prediction server.
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DOI：
10.1093/nar/gkn238
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发表时间：
2008-07-01
影响因子：
14.9
通讯作者：
Barton GJ
中科院分区：
文献类型：
--
作者：
Cole C;Barber JD;Barton GJ
Jpred（http：//www.compbio.dundee.ac.uk/jpred）是由Jnet算法驱动的二级结构预测服务器。Jpred每周为50多个国家的用户进行超过1000次预测。最近更新的Jnet算法提供了二级结构的三态（α-螺旋、β-链和卷曲）预测，准确度为81.5%。给定单个蛋白质序列或多个序列比对，Jpred推导出二级结构和溶剂可及性的预测的比对谱。这些预测以彩色HTML、纯文本、XML、PDF和Jalview对齐编辑器的形式呈现，以便灵活地查看和应用数据。新的Jpred 3服务器包括显著的可用性改进，包括更清晰的进度反馈或提交请求的失败。功能改进包括批量提交序列、通过电子邮件汇总结果和更新检索数据库。新的软件管道将使Jnet/Jpred能够继续与SCOP和UniProt的主要更新同步更新，从而确保Jpred 3将保持高精度预测。
Jpred (http://www.compbio.dundee.ac.uk/jpred) is a secondary structure prediction server powered by the Jnet algorithm. Jpred performs over 1000 predictions per week for users in more than 50 countries. The recently updated Jnet algorithm provides a three-state (α-helix, β-strand and coil) prediction of secondary structure at an accuracy of 81.5%. Given either a single protein sequence or a multiple sequence alignment, Jpred derives alignment profiles from which predictions of secondary structure and solvent accessibility are made. The predictions are presented as coloured HTML, plain text, PostScript, PDF and via the Jalview alignment editor to allow flexibility in viewing and applying the data. The new Jpred 3 server includes significant usability improvements that include clearer feedback of the progress or failure of submitted requests. Functional improvements include batch submission of sequences, summary results via email and updates to the search databases. A new software pipeline will enable Jnet/Jpred to continue to be updated in sync with major updates to SCOP and UniProt and so ensures that Jpred 3 will maintain high-accuracy predictions.
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通讯作者：
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