Effects of exercise on mobility in obese and nonobese older adults.
Effects of exercise on mobility in obese and nonobese older adults.
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DOI：
10.1038/oby.2009.317
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发表时间：
2010-06
期刊：
影响因子：
6.9
通讯作者：
Pahor, Marco
中科院分区：
文献类型：
--
作者：
Manini, Todd M.;Newman, Anne B.;Fielding, Roger;Blair, Steven N.;Perri, Michael G.;Anton, Stephen D.;Goodpaster, Bret C.;Katula, Jeff A.;Rejeski, Walter J.;Kritchevsky, Stephen B.;Hsu, Fang-Chi;Pahor, Marco
再加上社会老龄化，肥胖患病率的上升很可能会增加未来身体残疾的负担。我们着手确定肥胖是否改变了旨在预防老年人活动障碍的身体活动干预的效果。有残疾风险的老年人（N = 424，年龄范围：70-88岁）被随机分配到12个月的体力活动（PA）干预，包括中等强度的有氧运动，力量，平衡和灵活性运动（每周150分钟）或成功的老化（SA）干预，包括每周的教育研讨会。使用体重指数≥ 30（n = 179）按肥胖对个体进行分层。运动功能评估为400米以上的正常步行速度和短距离体能测试（SPPB）评分，包括短距离步行、平衡测试和椅子上升。在12个月的监督训练中，肥胖和非肥胖受试者的出勤率和步行时间总量相似，没有观察到体重变化。PA组中的非肥胖参与者在400米步行速度方面有显着增加（+1.5%），而SA组的参与者则下降（-4.3%）。相比之下，无论分配给他们的干预组如何，肥胖者都有所下降（PA：-3.1%; SA：-4.9%）。然而，肥胖（PA：+13.5%; SA：+2.5%）和非肥胖老年人（PA：+18.6%; SA：+6.1%）的SPPB评分在PA后增加。中等强度的PA干预可以改善老年人的身体功能，但其积极作用会随着肥胖而减弱。
Coupled with an aging society, the rising obesity prevalence is likely to increase the future burden of physical disability. We set out to determine whether obesity modified the effects of a physical activity intervention designed to prevent mobility disability in older adults. Older adults at risk for disability (N = 424, age range: 70-88 years) were randomized to a 12 month physical activity (PA) intervention involving moderate intensity aerobic, strength, balance and flexibility exercise (150 min per week) or a successful aging (SA) intervention involving weekly educational workshops. Individuals were stratified by obesity using a body mass index ≥ 30 (n = 179). Mobility function was assessed as usual walking speed over 400 meters and scores on a short physical performance battery (SPPB), which includes short distance walking, balance tests and chair rises. Over 12 months of supervised training, the attendance and total amount of walking time was similar between obese and non-obese subjects and no weight change was observed. Non-obese participants in the PA group had significant increases in 400 meter walking speed (+1.5%), while their counterparts in the SA group declined (−4.3%). In contrast, obese individuals declined regardless of their assigned intervention group (PA: −3.1%; SA: −4.9%). SPPB scores, however, increased following PA in both obese (PA: +13.5%; SA: +2.5%) and non-obese older adults (PA: +18.6%; SA: +6.1%). A moderate intensity PA intervention improves physical function in older adults, but the positive benefits are attenuated with obesity.
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DOI：
10.1093/gerona/62.6.616
发表时间：
2007-06-01
影响因子：
5.1
作者：
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通讯作者：
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影响因子：
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作者：
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作者：
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DOI：
10.1111/j.1532-5415.2007.01632.x
发表时间：
2008-04-01
影响因子：
6.3
作者：
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通讯作者：
Harris, Tamara B.
影响因子：
2.2
作者：
Rejeski, WJ;Fielding, RA;Pahor, M
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Pahor, M