Advances in assessment of bone porosity, permeability and interstitial fluid flow.
Advances in assessment of bone porosity, permeability and interstitial fluid flow.
复制标题
DOI：
10.1016/j.jbiomech.2012.10.025
复制
发表时间：
2013-01-18
影响因子：
2.4
通讯作者：
Cowin SC
中科院分区：
文献类型：
--
作者：
Cardoso L;Fritton SP;Gailani G;Benalla M;Cowin SC
这篇文章回顾了最近的研究，以评估骨组织的孔隙率和渗透性，目的是了解间质液的运动。骨组织力学传导被认为是由于腔隙-小管孔隙中邻近树突状细胞结构的间质孔隙液的通过而发生的。间质液的运动对于骨细胞的营养也是必要的。本综述将重点介绍与骨间质液流量评估相关的四个主题。首先，成像技术的优势和局限性，以可视化骨孔隙度和建筑在几个长度尺度进行了总结。其次，最近的努力来衡量血管孔隙度和腔隙小管微结构进行了讨论。第三，研究与测量和估计的流体压力和渗透性的血管和腔隙-小管域进行了总结。第四，最近的发展模型来表示骨孔隙之间的流体交换的描述。
This contribution reviews recent research performed to assess the porosity and permeability of bone tissue with the objective of understanding interstitial fluid movement. Bone tissue mechanotransduction is considered to occur due to the passage of interstitial pore fluid adjacent to dendritic cell structures in the lacunar-canalicular porosity. The movement of interstitial fluid is also necessary for the nutrition of osteocytes. This review will focus on four topics related to improved assessment of bone interstitial fluid flow. First, the advantages and limitations of imaging technologies to visualize bone porosities and architecture at several length scales are summarized. Second, recent efforts to measure the vascular porosity and lacunar-canalicular microarchitecture are discussed. Third, studies associated with the measurement and estimation of the fluid pressure and permeability in the vascular and lacunar-canalicular domains are summarized. Fourth, the development of recent models to represent the interchange of fluids between the bone porosities is described.
登录
查看更多内容
影响因子：
2.4
作者：
Anderson, Eric J.;Tate, Melissa L. Knothe
通讯作者：
Tate, Melissa L. Knothe
影响因子：
4.2
作者：
Cooper, DML;Matyas, JR;Hallgrimsson, B
通讯作者：
Hallgrimsson, B
DOI：
10.1098/rsta.2009.0099
发表时间：
2009-09-13
影响因子：
5
作者：
Cowin, Stephen C.;Gailani, Gaffar;Benalla, Mohammed
通讯作者：
Benalla, Mohammed
影响因子：
3.5
作者：
Benalla, M.;Cardoso, L.;Cowin, S. C.
通讯作者：
Cowin, S. C.
影响因子：
--
作者：
Cooper, D. M. L.;Turinsky, A. L.;Hallgrimsson, B.
通讯作者：
Hallgrimsson, B.