Impact of physical exercise programs in breast cancer survivors on health-related quality of life, physical fitness, and body composition: Evidence from systematic reviews and meta-analyses.
Impact of physical exercise programs in breast cancer survivors on health-related quality of life, physical fitness, and body composition: Evidence from systematic reviews and meta-analyses.
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DOI：
10.3389/fonc.2022.955505
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发表时间：
2022
影响因子：
4.7
通讯作者：
Macedo, Ana
中科院分区：
文献类型：
--
作者：
Joaquim, Ana;Leao, Ines;Antunes, Pedro;Capela, Andreia;Viamonte, Sofia;Alves, Alberto J. J.;Helguero, Luisa A.;Macedo, Ana
乳腺癌是全世界最常见的癌症，尽管其治疗取得了显著进展，但幸存者的生活质量受到与治疗相关的副作用的阻碍，这些副作用损害了心理社会和生理结果。近年来，几项研究证实了体育锻炼对乳腺癌幸存者的好处。体育锻炼减少治疗相关不良事件的影响，以促进更好的生活质量和功能结果。本研究旨在对体育锻炼对乳腺癌幸存者与健康相关的生活质量、心肺功能、肌肉力量和身体成分的影响进行系统的综述和荟萃分析。从2010年1月至2022年10月，对PubMed和Cochrane数据库进行系统综述和荟萃分析。主要焦点是确定接受根治性治疗(手术和/或放射治疗和/或化疗)的乳腺癌幸存者进行体育锻炼的有效性。两位评价者独立筛选文献，提取数据，并评估纳入研究中的偏倚风险。总共确定了101项研究，其中12项用于最终分析。符合条件的研究包括9项系统评价/荟萃分析、1项荟萃分析/荟萃回归和2项系统性评价。每次综述中纳入的随机临床试验的数量从11个到63个不等，参与人数从214个到5761个。在符合条件的研究中，83.3%(10项研究)报道了不同体育锻炼干预措施对健康相关生活质量的积极和显著影响。体育锻炼还改善了心肺健康(3项研究；25%)，并显示出在减轻体重(3项研究，25%)和腰围(4项研究，33.3%)方面有效。我们的结果表明，体育锻炼是一种有效的策略，对乳腺癌幸存者的生活质量、心肺健康和身体成分都有积极的影响。医疗保健专业人员应促进采用体育锻炼干预措施，以在乳腺癌治疗后实现更好的健康结果。、标识INPLASY2022110053。
Breast cancer is the most common cancer worldwide, and despite remarkable progress in its treatment, the survivors’ quality of life is hampered by treatment-related side effects that impair psychosocial and physiological outcomes. Several studies have established the benefits of physical exercise in breast cancer survivors in recent years. Physical exercise reduces the impact of treatment-related adverse events to promote a better quality of life and functional outcomes. This study aims to provide an overview of systematic reviews and meta-analyses on the effect of physical exercise on the health-related quality of life, cardiorespiratory fitness, muscle strength, and body composition of breast cancer survivors. PubMed and Cochrane databases were searched for systematic reviews and meta-analyses from January 2010 to October 2022. The main focus was ascertaining the effectiveness of physical exercise in breast cancer survivors undergoing curative treatment (surgery and/or radiotherapy and/or chemotherapy). Two reviewers independently screened the literature, extracted the data, and assessed the risk of bias in the included studies. A total of 101 studies were identified, and 12 were yielded for final analysis. The eligible studies included nine systematic reviews/meta-analyses, one meta-analysis/meta-regression, and two systematic reviews. The number of randomised clinical trials included in each review varied from 11 to 63, and the number of participants was from 214 to 5761. A positive and significant effect of different physical exercise interventions on health-related quality of life was reported in 83.3% (10 studies) of the eligible studies. Physical exercise also improved cardiorespiratory fitness (3 studies; 25%) and showed to be effective in reducing body weight (3 studies; 25%) and waist circumference (4 studies; 33.3%). Our results suggest that physical exercise is an effective strategy that positively affects breast cancer survivors’ quality of life, cardiorespiratory fitness, and body composition. Healthcare professionals should foster the adoption of physical exercise interventions to achieve better health outcomes following breast cancer treatments. , identifier INPLASY2022110053.
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影响因子：
3.3
作者：
Amatya B;Khan F;Galea MP
通讯作者：
Galea MP
DOI：
10.1007/s11136-021-02926-x
发表时间：
2022-04
期刊：
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
影响因子：
--
作者：
Kannan P;Lam HY;Ma TK;Lo CN;Mui TY;Tang WY
通讯作者：
Tang WY
DOI：
10.1016/j.ejon.2004.03.007
发表时间：
2005-03-01
期刊：
European journal of oncology nursing : the official journal of European Oncology Nursing Society
影响因子：
--
作者：
Campbell, Anna;Mutrie, Nanette;Kearney, Nora
通讯作者：
Kearney, Nora
影响因子：
3.7
作者：
Jones, Jennifer M.;Olson, Karin;Howell, Doris
通讯作者：
Howell, Doris
影响因子：
5.2
作者：
De Luca, V.;Minganti, C.;Parisi, A.
通讯作者：
Parisi, A.