The microRNA-regulated SBP-Box transcription factor SPL3 is a direct upstream activator of LEAFY, FRUITFULL, and APETALA1.

The microRNA-regulated SBP-Box transcription factor SPL3 is a direct upstream activator of LEAFY, FRUITFULL, and APETALA1.
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microRNA 调节的 SBP-Box 转录因子 SPL3 是 LEAFY、FRUITFULL 和 APETALA1 的直接上游激活剂。

DOI:
10.1016/j.devcel.2009.06.007
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发表时间:
2009-08
期刊:
影响因子:
11.8
通讯作者:
Wagner, Doris
Wagner, Doris
中科院分区:
生物学1区
文献类型:
--
作者:
Yamaguchi, Ayako;Wu, Miin-Feng;Yang, Li;Wu, Gang;Poethig, R. Scott;Wagner, Doris

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何时开花是一个发育决定,深刻影响开花植物的适应性。在拟南芥中,这一决定最终由转录因子 LEAFY (LFY)、FRUITFULL (FUL) 和 APETALA1 (AP1) 的诱导和后续活性控制。尽管它们非常重要,但我们目前对 LFY、FUL 和 AP1 表达调控的理解仍然不完整。我们在此表明​​,所有三个基因均由 microRNA 靶向转录因子 SQUAMOSA PROMOTER BINDING PROTEIN-LIKE 3 (SPL3) 直接激活。我们的研究结果表明,SPL3 与其他 microRNA 调节的 SPL 转录因子一起作用,控制花形成的时间。此外,已确定的 SPL 活动定义了控制这一重要发育决策的独特途径。
When to form flowers is a developmental decision that profoundly impacts the fitness of flowering plants. In Arabidopsis this decision is ultimately controlled by the induction and subsequent activity of the transcription factors LEAFY (LFY), FRUITFULL (FUL) and APETALA1 (AP1). Despite their central importance, our current understanding of the regulation of LFY, FUL and AP1 expression is still incomplete. We show here that all three genes are directly activated by the microRNA targeted transcription factor SQUAMOSA PROMOTER BINDING PROTEIN-LIKE 3 (SPL3). Our findings suggest that SPL3 acts together with other microRNA-regulated SPL transcription factors to control the timing of flower formation. Moreover, the identified SPL activity defines a distinct pathway in control of this vital developmental decision.
用于分析和识别共同调节基因的Athamap Web工具。
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