Endometrial polyps affect uterine receptivity.
Endometrial polyps affect uterine receptivity.
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DOI:
10.1016/j.fertnstert.2010.12.034
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发表时间:
2011-06-30
影响因子:
6.7
通讯作者:
Taylor, Hugh S.
中科院分区:
文献类型:
--
作者:
Rackow, Beth W.;Jorgensen, Elisa;Taylor, Hugh S.
This case-control study evaluated the effect of hysteroscopically identified endometrial polyps on endometrium using HOXA10 and HOX11, known molecular markers of endometrial receptivity. Uteri with endometrial polyps demonstrated a marked decrease in HOXA10 and HOXA11mRNA levels that may impair implantation; these findings suggest a molecular mechanism to support clinical findings of diminished pregnancy rates in women with endometrial polyps.
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