Effects of exercise-based pulmonary rehabilitation on severe/very severe COPD: a systematic review and meta-analysis.
Effects of exercise-based pulmonary rehabilitation on severe/very severe COPD: a systematic review and meta-analysis.
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DOI：
10.1177/17534666231162250
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发表时间：
2023-01
影响因子：
4.3
通讯作者：
Xie, Yang
中科院分区：
文献类型：
--
作者：
He, Wenqing;Wang, Jiajia;Feng, Zhenzhen;Li, Jiansheng;Xie, Yang
关键词：
肺康复（pulmonary rehabilitation，PR）已被认为是治疗各种呼吸系统疾病的有效方法。然而，基于运动的PR对重度/极重度慢性阻塞性肺疾病（COPD）患者的影响尚不清楚。本综述旨在探讨运动PR对重度/极重度COPD患者的影响。检索了PubMed、Embase、科克伦图书馆、Web of Science和ClinicalTrials.gov数据库，检索时间从开始到2022年12月23日，无语言限制。纳入了研究基于运动的PR对重度/极重度COPD患者影响的随机对照试验（RCT）。独立进行研究选择、数据提取和偏倚风险评估。采用RevMan软件（版本5.3）进行Meta分析。证据的质量采用建议评估、发展和评价系统的分级进行评级。识别了6项研究（263例患者）。与对照组相比，6 min步行距离[MD = 52.91，95%CI（3.80，102.03）]，圣乔治呼吸问卷总分[MD = −7.70，95% CI（−14.32，−1.08）]和博格量表评分[MD = −0.68，95%CI（−1.28，−0.08）]均有所改善。圣乔治呼吸问卷和博格量表评分分别评定为“中等质量”和“低质量”，6分钟步行距离评定为“极低质量”。以运动为基础的PR可改善重度/极重度COPD患者的运动能力、生活质量和呼吸困难，可作为一种辅助治疗。需要高质量、大样本的随机对照试验。本系统性综述和荟萃分析方案在PROSPERO进行了前瞻性注册（编号CRD 42022294085）。
Pulmonary rehabilitation (PR) has been considered to be an effective treatment method for various respiratory diseases. However, the effects of exercise-based PR on patients with severe/very severe chronic obstructive pulmonary disease (COPD) are unclear. This review aimed to investigate the effects of exercise-based PR on patients with severe/very severe COPD. PubMed, Embase, Cochrane Library, Web of Science, and ClinicalTrials.gov databases were searched from inception to December 23, 2022, without language restrictions. Randomized controlled trials (RCTs) investigating the effects of exercise-based PR on patients with severe/very severe COPD were included. Study selection, data extraction, and risk of bias assessment were conducted independently. RevMan software (version 5.3) was used for meta-analysis. The quality of evidence was rated using the Grading of Recommendations Assessment, Development and Evaluation system. Six studies (263 patients) were identified. Compared with the control group, the 6-min walking distance [MD = 52.91, 95% CI (3.80, 102.03)], the St. George’s Respiratory Questionnaire total scores [MD = −7.70, 95% CI (−14.32, −1.08)] and the Borg scale scores [MD = −0.68, 95% CI (−1.28, −0.08)] in the experimental group improved, respectively. The St. George’s Respiratory Questionnaire and Borg scale scores were rated as ‘moderate quality’ and ‘low quality’, respectively, and the 6-min walking distance was rated as ‘very low quality’. Exercise-based PR may improve the exercise capacity, quality of life and dyspnea of patients with severe/very severe COPD, which can be regarded as an adjuvant treatment. High quality and large sample RCTs are needed. This systematic review and meta-analysis protocol was prospectively registered with PROSPERO (No. CRD42022294085).
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影响因子：
15.8
作者：
Moher D;Liberati A;Tetzlaff J;Altman DG;PRISMA Group
通讯作者：
PRISMA Group
DOI：
10.1249/00005768-198205000-00012
发表时间：
1982-01-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
BORG, GAV
通讯作者：
BORG, GAV
影响因子：
1.7
作者：
Nyberg, Andre;Lindstrom, Britta;Wadell, Karin
通讯作者：
Wadell, Karin
影响因子：
10
作者：
Newall, C;Stockley, RA;Hill, SL
通讯作者：
Hill, SL
DOI：
10.1097/hcr.0000000000000109
发表时间：
2015-05-01
影响因子：
3.8
作者：
Mkacher, Wajdi;Mekki, Marwa;Trabelsi, Yassine
通讯作者：
Trabelsi, Yassine