Malaria in Cambodia: A Retrospective Analysis of a Changing Epidemiology 2006-2019.
Malaria in Cambodia: A Retrospective Analysis of a Changing Epidemiology 2006-2019.
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柬埔寨的疟疾：2006-2019年流行病学变化的回顾性分析。
DOI：
10.3390/ijerph18041960
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发表时间：
2021-02-18
影响因子：
--
通讯作者：
Tol B
中科院分区：
文献类型：
--
作者：
Chhim S;Piola P;Housen T;Herbreteau V;Tol B
背景：在柬埔寨，随着流行病学的变化和抗疟药的耐药性，疟疾持续存在。这项研究旨在描述2006年至2019年柬埔寨疟疾的空间演变情况。方法：我们对柬埔寨所有政府卫生保健机构现有的疟疾数据进行了二次分析。疟疾的流行病学以性别、年龄、季节性和物种来描述。利用泊松模型对区域层面的空间集群进行了识别。结果：总体而言，发病率从2006年的7.4例/1000人下降到2019年的1.9例/1000人。女性的下降幅度很大，从6.7 /1000降至0.6/1000。15-49岁的成年人在所有年龄组中疟疾发病率最高。确诊病例中恶性疟原虫+混合型的比例从2006年的87.9% （n = 67489）下降到2019年的16.6% （n = 5290）。在所有国家边界的森林省份均检测到恶性疟+混合型和间日疟+混合型聚集性病例。结论：2019年恶性疟原虫病例明显减少，应保持强化计划。间日疟病例也有所下降，尽管不那么明显。应优先考虑旨在预防间日疟原虫新发感染和复发的干预措施。所有发现的疟疾病例都应由国家监测系统监测，以避免出现误导性趋势。
Background: In Cambodia, malaria persists with changing epidemiology and resistance to antimalarials. This study aimed to describe how malaria has evolved spatially from 2006 to 2019 in Cambodia. Methods: We undertook a secondary analysis of existing malaria data from all government healthcare facilities in Cambodia. The epidemiology of malaria was described by sex, age, seasonality, and species. Spatial clusters at the district level were identified with a Poisson model. Results: Overall, incidence decreased from 7.4 cases/1000 population in 2006 to 1.9 in 2019. The decrease has been drastic for females, from 6.7 to 0.6/1000. Adults aged 15–49 years had the highest malaria incidence among all age groups. The proportion of Plasmodium (P.) falciparum + Mixed among confirmed cases declined from 87.9% (n = 67,489) in 2006 to 16.6% (n = 5290) in 2019. Clusters of P. falciparum + Mixed and P. vivax + Mixed were detected in forested provinces along all national borders. Conclusions: There has been a noted decrease in P. falciparum cases in 2019, suggesting that an intensification plan should be maintained. A decline in P. vivax cases was also noted, although less pronounced. Interventions aimed at preventing new infections of P. vivax and relapses should be prioritized. All detected malaria cases should be captured by the national surveillance system to avoid misleading trends.
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影响因子：
3
作者：
Aregawi M;Malm KL;Wahjib M;Kofi O;Allotey NK;Yaw PN;Abba-Baffoe W;Segbaya S;Owusu-Antwi F;Kharchi AT;Williams RO;Saalfeld M;Workneh N;Shargie EB;Noor AM;Bart-Plange C
通讯作者：
Bart-Plange C
影响因子：
15.8
作者：
Katureebe A;Zinszer K;Arinaitwe E;Rek J;Kakande E;Charland K;Kigozi R;Kilama M;Nankabirwa J;Yeka A;Mawejje H;Mpimbaza A;Katamba H;Donnelly MJ;Rosenthal PJ;Drakeley C;Lindsay SW;Staedke SG;Smith DL;Greenhouse B;Kamya MR;Dorsey G
通讯作者：
Dorsey G
影响因子：
5.7
作者：
Chu CS;White NJ
通讯作者：
White NJ
降雨量变化导致中国安徽省疟疾卷土重来
影响因子：
3.7
作者：
Gao HW;Wang LP;Liang S;Liu YX;Tong SL;Wang JJ;Li YP;Wang XF;Yang H;Ma JQ;Fang LQ;Cao WC
通讯作者：
Cao WC
柬埔寨恶性疟原虫疟疾中的双氢青蒿素-哌喹抗药性：一项多地点前瞻性队列研究。
DOI：
10.1016/s1473-3099(15)00487-9
发表时间：
2016-03
期刊：
The Lancet. Infectious diseases
影响因子：
--
作者：
Amaratunga C;Lim P;Suon S;Sreng S;Mao S;Sopha C;Sam B;Dek D;Try V;Amato R;Blessborn D;Song L;Tullo GS;Fay MP;Anderson JM;Tarning J;Fairhurst RM
通讯作者：
Fairhurst RM