Phylogenetic analysis reveals dynamic evolution of the poly(A)-binding protein gene family in plants.
Phylogenetic analysis reveals dynamic evolution of the poly(A)-binding protein gene family in plants.
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DOI：
10.1186/s12862-014-0238-4
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发表时间：
2014-11-25
影响因子：
3.4
通讯作者：
Liu R
中科院分区：
文献类型：
--
作者：
Gallie DR;Liu R
多聚腺苷酸结合蛋白（PABP）与真核生物mRNA的多聚腺苷酸尾结合，通过与真核生物翻译起始因子（eIF）4G和eIF 4 B的相互作用来维持mRNA的完整性，同时促进蛋白质合成。PABP在酵母和海藻中由单个基因编码，但在植物进化过程中，PABP基因家族大幅扩展，经历了序列分化成三个亚类，并获得了基因家族成员表达的组织特异性。虽然这种变化表明功能的专业化，家庭的大小和序列的分歧复杂的理解，基因家族成员可能是基础的，可能代表最近的家庭扩大，以满足特定的物种形成的需要。在这里，我们研究了植物PABP基因家族的进化，以提供深入了解这些方面的家庭，可能会产生线索到个别家庭成员的功能。随着淡水藻类的出现，PABP基因家族已扩大到两个成员，在非维管植物中则有四个成员。在石松植物中，产生特定纲成员的第一个序列趋异发生。该基因家族的最早成员与那些表达仅限于生殖组织的现代成员具有最大的相似性，这表明支持生殖相关基因表达是该家族最保守的功能。一个与现代植物相关成员有相似性的家族成员首先出现在裸子植物中。在开花植物的进化过程中，对生殖相关和营养相关成员的进一步阐述发生了。植物PABP基因家族的扩展在土地殖民化之前就开始了。随着石松植物的进化，在高等植物中出现了第一类仅在生殖组织表达的成员。第二类成员的表达是植物相关的出现在裸子植物和所有三个现代类已经完全进化的第一个已知的基础被子植物的外观。在随后的进化过程中，特别是在菊科中，每个PABP类的大小都经历了进一步的扩展，表明该科正在经历动态进化。本文的在线版本（doi：10.1186/s12862-014-0238-4）包含补充材料，可供授权用户使用。
The poly(A)-binding protein (PABP) binds the poly(A) tail of eukaryotic mRNAs and functions to maintain the integrity of the mRNA while promoting protein synthesis through its interaction with eukaryotic translation initiation factor (eIF) 4G and eIF4B. PABP is encoded by a single gene in yeast and marine algae but during plant evolution the PABP gene family expanded substantially, underwent sequence divergence into three subclasses, and acquired tissue-specificity in gene family member expression. Although such changes suggest functional specialization, the size of the family and its sequence divergence have complicated an understanding of which gene family members may be foundational and which may represent more recent expansions of the family to meet the specific needs of speciation. Here, we examine the evolution of the plant PABP gene family to provide insight into these aspects of the family that may yield clues into the function of individual family members. The PABP gene family had expanded to two members by the appearance of fresh water algae and four members in non-vascular plants. In lycophytes, the first sequence divergence yielding a specific class member occurs. The earliest members of the gene family share greatest similarity to those modern members whose expression is confined to reproductive tissues, suggesting that supporting reproductive-associated gene expression is the most conserved function of this family. A family member sharing similarity to modern vegetative-associated members first appears in gymnosperms. Further elaboration of the reproductive-associated and vegetative-associated members occurred during the evolution of flowering plants. Expansion of the plant PABP gene family began prior to the colonization of land. By the evolution of lycophytes, the first class member whose expression is confined to reproductive tissues in higher plants had appeared. A second class member whose expression is vegetative-associated appeared in gymnosperms and all three modern classes had fully evolved by the appearance of the first known basal angiosperm. The size of each PABP class underwent further expansion during subsequent evolution, especially in the Brassicaceae, suggesting that the family is undergoing dynamic evolution. The online version of this article (doi:10.1186/s12862-014-0238-4) contains supplementary material, which is available to authorized users.
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影响因子：
4.3
作者：
Altschul SF;Wootton JC;Zaslavsky E;Yu YK
通讯作者：
Yu YK
DOI：
10.1073/pnas.77.4.1890
发表时间：
1980-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
--
作者：
BAER, BW;KORNBERG, RD
通讯作者：
KORNBERG, RD
影响因子：
2.9
作者：
Cheng, Shijun;Gallie, Daniel R.
通讯作者：
Gallie, Daniel R.
DOI：
10.1073/pnas.90.14.6686
发表时间：
1993-07-15
影响因子：
11.1
作者：
BELOSTOTSKY, DA;MEAGHER, RB
通讯作者：
MEAGHER, RB
影响因子：
4.8
作者：
Bushell, M;Wood, W;Clemens, MJ
通讯作者：
Clemens, MJ