STEPPED CARE: AN EVIDENCE-BASED APPROACH TO DRUG THERAPY

STEPPED CARE: AN EVIDENCE-BASED APPROACH TO DRUG THERAPY
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分级护理:基于证据的药物治疗方法

DOI:
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发表时间:
2002
期刊:
影响因子:
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通讯作者:
Jonathan Cree
Jonathan Cree
中科院分区:
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文献类型:
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作者:
Cara Lawless;Jonathan Cree

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编者按:本月我们继续推出《循序渐进的护理:药物治疗的循证方法》。这些文章旨在为家庭医生在日常实践中遇到的药物治疗问题提供简明的答案。该功能的格式将遵循助记步骤:安全性(对患者和提供者关心的不良反应的分析)、耐受性(大型临床试验的合并辍学率)、有效性(药物的效果如何以及在哪些患者群体中[S])和价格(药物成本,但也包括治疗的成本效益)。因此,这个名字被命名为阶梯式护理。自从麦克马斯特大学的信息学先驱引入循证医学以来,斯劳森和他的同事们将其带入了主流家庭医学教育和实践。这一功能旨在推进在医疗实践中寻求真相的使命。作者将以结构化的格式提供信息,使读者能够以一种有助于医生(和患者)做出明智决定的方式深入了解治疗问题的实质。这些条款将不鼓励使用以疾病为导向的证据(DOE)来做出治疗决定。例如,血压降低、血红蛋白A1c降低等等。我们将纳入以POEMS患者为导向的研究,以证明其重要性(心肌梗死、疼痛、中风、死亡率等),以期为我们的患者提供最实用、最合适和最科学的治疗方法。观察单个患者的益处所需的治疗数量也将包括在内,以相对容易理解的术语定义优势。有时,这种努力会令人沮丧。尽管生物医学文献数量庞大,但它并不总是支持临床医生的做法。我们将避免做出没有诗歌支持的结论。然而,诗歌应该结合到临床实践中。剩下的就看读者了。将诗歌与理性思维、临床经验以及重要的病人喜好融合在一起,可以成为医学艺术的精髓。我们希望您会发现这些新文章很有用,而且容易阅读。欢迎您的意见和建议。您可以通过JABFP编辑部联系编辑。我们希望这些文章能为您提供可应用于日常实践的有用信息,并期待您的反馈。
Editors’ Note: This month we continue the feature STEPped Care: An Evidence-Based Approach to Drug Therapy. These articles are designed to provide concise answers to the drug therapy questions that family physicians encounter in their daily practice. The format of the feature will follow the mnemonic STEP: safety (an analysis of adverse effects that patients and providers care about), tolerability (pooled dropout rates from large clinical trials), effectiveness (how well the drugs work and in what patient population[s]), and price (costs of drug, but also cost effectiveness of therapy). Hence, the name STEPped Care. Since the informatics pioneers at McMaster University introduced evidence-based medicine, Slawson and colleagues have brought it to mainstream family medicine education and practice. This feature is designed to further the mission of searching for the truth in medical practice. Authors will provide information in a structured format that allows the readers to get to the meat of a therapeutic issue in a way that can help physicians (and patients) make informed decisions. The articles will discourage the use of disease-oriented evidence (DOE) to make treatment decisions. Examples of DOEs include blood pressure lowering, decreases in hemoglobin A1c, and so on. We will include studies that are POEMs patientoriented evidence that matters (myocardial infarctions, pain, strokes, mortality, etc) with the goal of offering our patients the most practical, appropriate, and scientifically substantiated therapies. Number needed to treat to observe benefit in a single patient will also be included as a way of defining advantages in terms that are relatively easy to understand. At times this effort will be frustrating. Even as vast as the biomedical literature is, it does not always support what clinicians do. We will avoid making conclusions that are not supported by POEMs. Nevertheless, POEMs should be incorporated into clinical practice. The rest is up to the reader. Blending POEMs with rational thought, clinical experience, and importantly, patient preferences can be the essence of the art of medicine. We hope you will find these new articles useful and easy to read. Your comments and suggestions are welcome. You may contact the editors through the editorial office of JABFP. We hope the articles provide you with useful information that can be applied in everyday practice, and we look forward to your feedback.
尼古丁口香糖剂量对尼古丁依赖程度的影响。
DOI: 10.1080/14622200050011303
发表时间: 2000
期刊: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
影响因子: --
作者:
Garvey,AJ;Kinnunen,T;Nordstrom,BL;Utman,CH;Doherty,K;Rosner,B;Vokonas,PS
通讯作者: Vokonas,PS
DOI: 10.1046/j.1460-9568.2002.01908.x
发表时间: 2002-02-01
影响因子: 3.4
作者:
Gong, LW;Gao, TM;Tong, ZQ
通讯作者: Tong, ZQ
DOI: 10.1161/01.str.28.11.2109
发表时间: 1997-11-01
期刊: STROKE
影响因子: 8.3
作者:
Brott, T;Broderick, J;Fong, WC
通讯作者: Fong, WC
DOI: 10.1161/01.str.28.11.2119
发表时间: 1997-11-01
期刊: STROKE
影响因子: 8.3
作者:
Brott, T;Broderick, J;Fong, WC
通讯作者: Fong, WC