Steroid use after the Kasai procedure for biliary atresia.
Steroid use after the Kasai procedure for biliary atresia.
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DOI:
10.1016/j.amjsurg.2010.01.014
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发表时间:
2010-05
影响因子:
3
通讯作者:
Goldin, Adam B.
中科院分区:
文献类型:
--
作者:
Lao, Oliver B.;Larison, Cindy;Garrison, Michelle;Healey, Patrick J.;Goldin, Adam B.
To describe patients undergoing the Kasai procedure at childrens hospitals, evaluate outcomes, and analyze the association of these outcomes with systemic steroid use. We identified biliary atresia patients (ICD-9 751.61) that underwent a Kasai procedure at free-standing children's hospitals in the Pediatric Health Information System database (2003-2008). We examined descriptive characteristics and used regression analyses to determine whether post-operative steroid usage was associated with length of stay, mortality, or cholangitis. Of the 516 children identified (40% male, 50% <2 months-old), 239 (46%) received peri-operative steroids. The mean total and post-operative length of stay was 14.5±19.7 days and 11.3±16.3 days, respectively. In our analysis, post-operative steroid use was significantly associated with a 3.5 day decrease in post-operative length of stay (95%CI 0.03-6.97). Peri-operative steroids after the Kasai procedure are associated with shorter post-operative length of stay. Work is needed to ascertain whether this relationship is causal.
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