Steroid use after the Kasai procedure for biliary atresia.

Steroid use after the Kasai procedure for biliary atresia.
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DOI:
10.1016/j.amjsurg.2010.01.014
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发表时间:
2010-05
影响因子:
3
通讯作者:
Goldin, Adam B.
Goldin, Adam B.
中科院分区:
医学3区
文献类型:
--
作者:
Lao, Oliver B.;Larison, Cindy;Garrison, Michelle;Healey, Patrick J.;Goldin, Adam B.

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To describe patients undergoing the Kasai procedure at childrens hospitals, evaluate outcomes, and analyze the association of these outcomes with systemic steroid use. We identified biliary atresia patients (ICD-9 751.61) that underwent a Kasai procedure at free-standing children's hospitals in the Pediatric Health Information System database (2003-2008). We examined descriptive characteristics and used regression analyses to determine whether post-operative steroid usage was associated with length of stay, mortality, or cholangitis. Of the 516 children identified (40% male, 50% <2 months-old), 239 (46%) received peri-operative steroids. The mean total and post-operative length of stay was 14.5±19.7 days and 11.3±16.3 days, respectively. In our analysis, post-operative steroid use was significantly associated with a 3.5 day decrease in post-operative length of stay (95%CI 0.03-6.97). Peri-operative steroids after the Kasai procedure are associated with shorter post-operative length of stay. Work is needed to ascertain whether this relationship is causal.
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