New directions in necrotizing enterocolitis with early-stage investigators.

New directions in necrotizing enterocolitis with early-stage investigators.
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DOI:
10.1038/s41390-020-1078-0
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发表时间:
2020-08
期刊:
影响因子:
3.6
通讯作者:
Good M
Good M
中科院分区:
医学3区
文献类型:
--
作者:
Markel TA;Martin CA;Chaaban H;Canvasser J;Tanner H;Denchik H;Good M

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2019年坏死性小肠结肠炎(NEC)研讨会扩大了NEC协会的目标,即将利益相关者聚集在一起,讨论尖端科学、潜在的治疗和预防措施,以及NEC的患者家庭视角。研讨会促进了讨论和知识分享,总体目标是创建“一个没有NEC的世界”。为了实现这一目标,有必要进行新的研究来推动科学的发展。在过去的十年里,几位著名的研究人员显著提高了我们对NEC病理生理学的理解,他们为下一代临床医生--资助进行NEC研究的科学家铺平了道路。这篇文章将强调这些年轻的临床科学家的贡献,他们试图阐明免疫、微生物和神经系统失调是如何导致NEC的病理生理学的。
The 2019 Necrotizing Enterocolitis (NEC) Symposium expanded upon the NEC Society’s goals of bringing stakeholders together to discuss cutting-edge science, potential therapeutics and preventative measures, as well as the patient-family perspectives of NEC. The Symposium facilitated discussions and shared knowledge with the overarching goal of creating “A World Without NEC.” To accomplish this goal, new research to advance the state of the science is necessary. Over the last decade, several established investigators have significantly improved our understanding of the pathophysiology of NEC and they have paved the way for the next generation of clinician-scientists funded to perform NEC research. This article will serve to highlight the contributions of these young clinician-scientists that seek to elucidate how immune, microbial and nervous system dysregulation contributes to the pathophysiology of NEC.
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