Nosocomial infections and risk factors in the intensive care unit of a teaching and research hospital: a prospective cohort study.
Nosocomial infections and risk factors in the intensive care unit of a teaching and research hospital: a prospective cohort study.
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DOI：
10.12659/msm.881750
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发表时间：
2011-05
期刊：
影响因子：
--
通讯作者：
Çolakoğlu S
中科院分区：
文献类型：
--
作者：
Ak O;Batirel A;Ozer S;Çolakoğlu S
目的了解我院重症监护病房（ICU）医院感染的发生率、危险因素及病原学情况，为制定医院感染控制策略提供依据。2008年在我院ICU进行了一项为期1年的医院感染（NI）监测前瞻性队列研究。在ICU住院6257天的1134例患者中，115例患者共发生135例NI，分布如下：36.3%菌血症、30.4%呼吸机相关肺炎（VAP）、18.5%导管相关尿路感染、7.4%中心静脉感染、5.9%皮肤感染和1.3%脑膜炎。医院感染发生率为21.6/1000病人日，医院感染发生率为25.6%。ICU住院时间、中心静脉置管、机械通气和气管切开是医院感染的危险因素。在所有NI中，112例（83%）经微生物学证实，68.8%的分离株为革兰氏阴性，27.6%为革兰氏阳性，3.6%为真菌。23例（17%）为临床定义的感染。最常见的分离微生物是铜绿假单胞菌（25%），其次是S。aureus（21.4%）、E.大肠埃希菌（18.7%）和A.鲍曼不动杆菌（16.9%）。血流是最常见的部位，革兰氏阴性菌是ICU感染最常见的报告原因。
To evaluate the incidence, risk factors and etiology of nosocomial infections (NIs) in the intensive care unit (ICU) of our hospital in order to improve our infection control policies. A 1-year prospective cohort study of nosocomial infection (NI) surveillance was conducted in our ICU in 2008. Out of 1134 patients hospitalized in the ICU for a period of 6257 days, 115 patients acquired a total of 135 NIs distributed as follows: 36.3% bacteremia, 30.4% ventilator-associated pneumonia (VAP), 18.5% catheter-associated urinary tract infection, 7.4% central-line infection, 5.9% cutaneous infection, and 1.3% meningitis. The incidence rate of NI was 21.6 in 1000 patient-days, and the rate of NI was 25.6%. Length of ICU stay, central venous catheterisation, mechanical ventilation and tracheostomy were statistically significant risk factors for NI. Of all NI, 112 (83%) were microbiologically-confirmed and 68.8% of the isolates were Gram-negative, 27.6% were Gram-positive, and 3.6% were fungi. 23 (17%) were clinically-defined infections. The most frequently isolated organism was P. aeruginosa (25%), followed by S. aureus (21.4%), E. coli (18.7%) and A. baumannii (16.9%). The bloodstream was the most common site and Gram-negatives were the most commonly reported causes of ICU infections.
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影响因子：
3.2
作者：
Aly, Nasser Yehia A.;Al-Mousa, Haifaa H.;Al Asar, El Sayed M.
通讯作者：
Al Asar, El Sayed M.
影响因子：
6.9
作者：
Urli, T;Perone, G;Candiani, A
通讯作者：
Candiani, A
影响因子：
--
作者：
Esen, S;Leblebicioglu, H
通讯作者：
Leblebicioglu, H
影响因子：
8.4
作者：
Markogiannakis, Haridimos;Pachylaki, Nikoleta;Katsaragakis, Stilianos
通讯作者：
Katsaragakis, Stilianos
影响因子：
8.8
作者：
de León-Rosales, SP;Molinar-Ramos, F;Vázquez-Ramos, VG
通讯作者：
Vázquez-Ramos, VG