Successful corticosteroid treatment for pleural effusion due to radiation-induced pleuritis after chemoradiotherapy in a patient with esophageal cancer
Successful corticosteroid treatment for pleural effusion due to radiation-induced pleuritis after chemoradiotherapy in a patient with esophageal cancer
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皮质类固醇成功治疗食管癌患者放化疗后放射性胸膜炎引起的胸腔积液
DOI：
10.1007/s13691-017-0293-y
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发表时间：
2017
影响因子：
0.7
通讯作者：
Kamei Takashi
中科院分区：
文献类型：
--
作者：
Kumagai Takuro;Nakano Toru;Matsushita Haruo;Jingu Keiichi;Ohuchi Noriaki;Kamei Takashi
同步放化疗（CRT）是治疗食管鳞状细胞癌（ESCC）的有效疗法之一，经CRT治疗的食管癌患者的总生存期有所改善。随着同时接受 CRT 治疗的长期幸存者数量的增加，更多的患者出现晚期毒性。延迟性不良事件（例如胸腔积液）有时是致命的，但对其治疗方法知之甚少。一名被诊断患有 ESCC 的 72 岁男性接受了明确的 CRT 治疗。他对 CRT 有完全反应，4 年后，他抱怨因胸腔积液引起呼吸困难。在该病例中，利尿剂和胸腔积液引流效果不佳。口服 30 mg 泼尼松龙后，胸膜腔内液体的再积聚得到控制，泼尼松龙剂量逐渐减少。皮质类固醇可能是放疗后迟发性胸腔积液的有效治疗方法，并且应被视为治疗难治性胸腔积液的一种选择。
Concurrent chemoradiotherapy (CRT) is one of the therapies with curative intent used to treat esophageal squamous cell carcinoma (ESCC), and overall survival of patients with esophageal carcinoma treated with CRT has improved. As the number of long-term survivors treated with concurrent CRT has increased, more patients experience late toxicities. A delayed adverse event, such as pleural effusion, is sometimes fatal, but little is known about its treatment. A 72-year-old man diagnosed with ESCC was treated with definitive CRT. He had a complete response to CRT, and 4 years later he complained of dyspnea, caused by pleural effusion. Diuretic agents and drainage of pleural effusion were not sufficiently effective in this case. After oral administration of 30 mg prednisolone, re-accumulation of fluid in the pleural space was controlled and the prednisolone dose was gradually tapered. Corticosteroids could be effective treatment for delayed pleural effusion after radiotherapy, and should be considered an option for treatment-refractory pleural effusion.
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霍奇金淋巴瘤治疗的后期效果。
DOI：
10.6004/jnccn.2006.0024
发表时间：
2006
期刊：
Journal of the National Comprehensive Cancer Network : JNCCN
影响因子：
--
作者：
D. Friedman;L. Constine
通讯作者：
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DOI：
10.2302/kjm.56.124
发表时间：
2007
期刊：
The Keio journal of medicine
影响因子：
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作者：
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A. Kubo
DOI：
10.1016/j.ijrobp.2009.07.1754
发表时间：
2010-03-01
影响因子：
7
作者：
Marks, Lawrence B.;Yorke, Ellen D.;Jackson, Andrew;Ten Haken, Randall K.;Constine, Louis S.;Eisbruch, Avraham;Bentzen, Soren M.;Nam, Jiho;Deasy, Joseph O.
通讯作者：
Deasy, Joseph O.
影响因子：
50.5
作者：
Hagelstein, V.;Ortland, I.;Jaehde, U.
通讯作者：
Jaehde, U.
早期给予甲泼尼龙或布洛芬可减少放射性心脏病兔的心肌羟脯氨酸
影响因子：
37.8
作者：
W. Reeves;D. Cunningham;E. Schwiter;A. Abt;S. Skarlatos;M. Wood;L. Whitesell
通讯作者：
L. Whitesell