Nipah virus encephalitis reemergence, Bangladesh.
Nipah virus encephalitis reemergence, Bangladesh.
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DOI：
10.3201/eid1012.040701
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发表时间：
2004-12
影响因子：
11.8
通讯作者：
Breiman RF
中科院分区：
文献类型：
--
作者：
Hsu VP;Hossain MJ;Parashar UD;Ali MM;Ksiazek TG;Kuzmin I;Niezgoda M;Rupprecht C;Bresee J;Breiman RF
孟加拉国的两次尼帕病毒脑炎暴发可能与人际传播有关。我们回顾性调查了2001年和2003年发生在孟加拉国Meherpur和Naogaon的两次脑炎暴发。我们收集了病人、他们的家庭接触者、随机选择的居民、医院工作人员和各种动物的血清样本。病例被分类为实验室确诊或可能病例。我们在梅尔普尔发现了13例（4例确诊，9例可能）；两户人家共有7人死亡。患者比非患者更有可能与其他患者密切接触或与病牛接触。在Naogaon，我们发现了12例（4例确诊，8例可能）；7例聚集在2个家庭。两只狐蝠有尼帕病毒抗体。医院工作人员的样本对尼帕病毒抗体呈阴性。这是1999年以来的首次疫情，表明可能通过与其他患者密切接触或暴露于共同来源而发生传播。建议监测和加强检测尼帕病毒感染的诊断能力。
Two Nipah virus encephalitis outbreaks in Bangladesh may be associated with person-to-person transmission. We retrospectively investigated two outbreaks of encephalitis in Meherpur and Naogaon, Bangladesh, which occurred in 2001 and 2003. We collected serum samples from persons who were ill, their household contacts, randomly selected residents, hospital workers, and various animals. Cases were classified as laboratory confirmed or probable. We identified 13 cases (4 confirmed, 9 probable) in Meherpur; 7 were in persons in two households. Patients were more likely than nonpatients to have close contact with other patients or have contact with a sick cow. In Naogaon, we identified 12 cases (4 confirmed, 8 probable); 7 were in persons clustered in 2 households. Two Pteropus bats had antibodies for Nipah virus. Samples from hospital workers were negative for Nipah virus antibodies. These outbreaks, the first since 1999, suggest that transmission may occur through close contact with other patients or from exposure to a common source. Surveillance and enhancement of diagnostic capacity to detect Nipah virus infection are recommended.
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影响因子：
11.8
作者：
Olson, JG;Rupprecht, C;Ksiazek, TG
通讯作者：
Ksiazek, TG
影响因子：
168.9
作者：
Paton, NI;Leo, YS;Ksiazek, TG
通讯作者：
Ksiazek, TG
影响因子：
5.8
作者：
Daniels, P;Ksiazek, T;Eaton, BT
通讯作者：
Eaton, BT
影响因子：
3.8
作者：
Halpin, K;Young, PL;Mackenzie, JS
通讯作者：
Mackenzie, JS
影响因子：
158.5
作者：
Goh, KJ;Tan, CT;Lam, SK
通讯作者：
Lam, SK