A prospective report on the prevalence of heart rate and blood pressure abnormalities in veterans with spinal cord injuries
A prospective report on the prevalence of heart rate and blood pressure abnormalities in veterans with spinal cord injuries
复制标题
关于脊髓损伤退伍军人心率和血压异常患病率的前瞻性报告
DOI：
10.1179/2045772313y.0000000109
复制
发表时间：
2013
期刊：
影响因子：
--
通讯作者：
M. Galea
中科院分区：
文献类型：
--
作者：
J. Wecht;C. Zhu;J. Weir;C. Yen;Christopher P. Renzi;M. Galea
摘要目的分散性心血管自主神经调节可能导致脊髓损伤（SCI）患者心率（HR）和血压（BP）异常发生率增加。此外，合并症和处方药使用可能会增加HR和BP异常。这些异常包括心动过缓、心动过速、低血压、高血压以及自主神经反射障碍和直立性低血压;其患病率未知。设计心率和血压数据测量期间，例行年度体检的64名退伍军人与SCI。记录坐位和仰卧位的HR和BP测量值，以记录体位的影响，并记录这些评估中的受试者内变异性。结果所有受试者均为慢性损伤（20 ± 14岁），四肢瘫痪（T：C3-C8）33例，高位截瘫（HP：T1-T6）9例，低位截瘫（LP：T7-L2）22例。无论体位如何，T组心动过缓的患病率增加，而HP和LP组心动过速的患病率增加。收缩期低血压在T组和HP组中比LP组更常见，并且位置效应在T组中最明显。收缩期高血压在T组和HP组中相当，但在LP组中的患病率是其两倍。观察到患有三种或三种以上疾病并处方三种或三种以上可能影响HR和BP的药物的个体的患病率增加。结论：分散的自主神经调节，共病的医疗条件和处方药的使用，在退伍军人SCI的结果在HR和BP异常，我们的数据表明，这些异常变化取决于损伤的水平和直立位。
Abstract Objective Decentralized autonomic cardiovascular regulation may lead to increased prevalence of heart rate (HR) and blood pressure (BP) abnormalities in veterans with SCI. In addition, comorbid medical conditions and prescription medication use may increase HR and BP abnormalities. These abnormalities include bradycardia, and tachycardia, hypotension, hypertension as well as autonomic dysreflexia and orthostatic hypotension; the prevalence of which is unknown. Design HR and BP data were measured during a routine annual physical examination in 64 veterans with SCI. Measurements of HR and BP were recorded in the seated and supine positions to document the influence of body position and to document intra-subject variability in these assessments. Results All subjects were chronically injured (20 ± 14 years), 33 subjects were tetraplegic (T: C3–C8), nine had high paraplegia (HP: T1–T6), and 22 had low paraplegia (LP: T7–L2). Regardless of position, the prevalence of bradycardia was increased in the T group, whereas prevalence of tachycardia was increased in the HP and LP groups. Systolic hypotension was more common in the T and HP groups than the LP group and positional effects were most evident in the T group. Systolic hypertension was comparable in the T and HP groups but was twice as prevalent in the LP group. Increased prevalence of individuals with three or more medical conditions and prescribed three or more medications which might influence HR and BP was observed. Conclusion Decentralized autonomic regulation, comorbid medical conditions, and prescription medication use in veterans with SCI result in HR and BP abnormalities; our data suggest that these abnormalities vary depending on the level of injury and orthostatic positioning.
影响因子：
4.8
作者：
GILLMAN, MW;KANNEL, WB;DAGOSTINO, RB
通讯作者：
DAGOSTINO, RB
DOI：
10.1093/geronj/45.4.p128
发表时间：
1990-07-01
期刊：
JOURNALS OF GERONTOLOGY
影响因子：
--
作者：
ELIAS, MF;ROBBINS, MA;PIERCE, TW
通讯作者：
PIERCE, TW