ILC2 frequency and activity are inhibited by glucocorticoid treatment via STAT pathway in patients with asthma.

ILC2 frequency and activity are inhibited by glucocorticoid treatment via STAT pathway in patients with asthma.
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哮喘患者中糖皮质激素治疗通过 STAT 通路抑制 ILC2 频率和活性

DOI:
10.1111/all.13438
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发表时间:
2018-09
期刊:
影响因子:
12.4
通讯作者:
Fu QL
Fu QL
中科院分区:
医学1区
文献类型:
--
作者:
Yu QN;Guo YB;Li X;Li CL;Tan WP;Fan XL;Qin ZL;Chen D;Wen WP;Zheng SG;Fu QL

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第2组先天性淋巴样细胞(ILC2)与哮喘密切相关。但目前尚缺乏关于糖皮质激素对哮喘患者ILC2影响的前瞻性研究。我们的目的是进行前瞻性研究,并评估哮喘患者糖皮质激素治疗后ILC2的活性。
Group 2 innate lymphoid cells (ILC2s) were closely associated with asthma. However, there were no perspective studies about the effects of glucocorticoid on ILC2s in asthma patients. Our objective was to perform a perspective study and evaluate the ILC2 activity after glucocorticoid therapy in asthma patients.
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