Epigenetic Regulation and Environmental Sex Determination in Cichlid Fishes.
Epigenetic Regulation and Environmental Sex Determination in Cichlid Fishes.
复制标题
DOI：
10.1159/000517197
复制
发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Hurd PL
中科院分区：
文献类型：
--
作者：
Renn SCP;Hurd PL
研究环境性别决定（ESD）在慈鲷提供了一个系统发育和比较的方法来了解进化的基本机制，其对上层系统的进化的影响，以及生活史策略的神经行为学。自然选择通常有利于父母平等地投资于男性和女性后代的发展，但当环境条件产生优势时，进化可能会倾向于偏离50：50的比例。许多种类的慈鲷表现出环境性别决定响应水化学（温度，pH值和氧浓度）。这些因素的相对强度和确切的相互作用因同系物而异，表明敏感性存在遗传差异。在大多数物种中，对极端环境的不太常见的性别的相当大的比例的存在强烈表明，存在一些遗传性别决定基因座与ESD因素平行作用。这些物种的性别决定和分化似乎并不导致最终和不可逆转的性命运的组织，而是由表观遗传因素控制的相互竞争的雄性决定和雌性决定遗传和激素网络之间的终身持续战斗。我们讨论了什么是，是不是，已知的性腺和性别差异在大脑中的分化背后的表观遗传机制。除了已被充分研究的罗非鱼物种，两个研究最好的侏儒慈鲷系统显示环境性别决定是南美属Apistogramma和西非属Pelvicachromis。这两个物种都表现出雄性变体，具有替代性的生殖策略。我们讨论了进一步的神经行为学的机会，这样的系统提供了替代生活史策略和其他行为变异的表观遗传学的研究。
Studying environmental sex determination (ESD) in cichlids provides a phylogenetic and comparative approach to understand the evolution of the underlying mechanisms, their impact on the evolution of the overlying systems, and the neuroethology of life history strategies. Natural selection normally favors parents who invest equally in the development of male and female offspring, but evolution may favor deviations from this 50:50 ratio when environmental conditions produce an advantage for doing so. Many species of cichlids demonstrate environmental sex determination in response to water chemistry (temperature, pH, and oxygen concentration). The relative strengths of, and the exact interactions between, these factors varies between congeners, demonstrating genetic variation in sensitivity. The presence of sizable proportions of the less common sex towards the environmental extremes in most species strongly suggests the presence of some genetic sex determining loci acting in parallel with the ESD factors. Sex determination and differentiation in these species does not seem to result in the organization of a final and irreversible sexual fate, so much as a life-long on-going battle between competing male determining and female determining genetic and hormonal networks governed by epigenetic factors. We discuss what is, and is not, known about the epigenetic mechanism behind the differentiation of both gonads and sex differences in the brain. Beyond the well studied tilapia species, the two best-studied dwarf cichlid systems showing environmental sex determination are the South American genus Apistogramma, and the West African genus Pelvicachromis. Both these species demonstrate male morphs with alternative reproductive tactics. We discuss the further neuroethology opportunities such systems provide to the study of epigenetics of alternative life history strategies and other behavioral variation.
登录
查看更多内容
影响因子：
3.9
作者：
Anastasiadi D;Esteve-Codina A;Piferrer F
通讯作者：
Piferrer F
影响因子：
7.2
作者：
Cheng X
通讯作者：
Cheng X
影响因子：
4.5
作者：
Bezault, Etienne;Clota, Frederic;Baroiller, Jean-Francois
通讯作者：
Baroiller, Jean-Francois
DOI：
10.1016/s0960-0760(01)00147-9
发表时间：
2001-12-01
影响因子：
4.1
作者：
Callard, GV;Tchoudakova, AV;Wood, E
通讯作者：
Wood, E
影响因子：
48
作者：
Angermueller C;Clark SJ;Lee HJ;Macaulay IC;Teng MJ;Hu TX;Krueger F;Smallwood S;Ponting CP;Voet T;Kelsey G;Stegle O;Reik W
通讯作者：
Reik W